Clinical Efficacy of Platelet-Rich Plasma on Allograft Transplantation after Core Decompression for Osteonecrosis of the Femoral Head
Journal Title: Journal of Orthopedics & Bone Disorders - Year 2017, Vol 1, Issue 4
Abstract
Purpose: This study explored the outcomes and clinical use of autologous, platelet-rich plasma (PRP) infusion after allograft bone transplantation for osteonecrosis of the femoral head (ONFH) by comparing the time to bone fusion and clinical symptoms. Method and Materials: From January 2008 to June 2015, 36 patients with a follow-up of at least 12 months were enrolled. 18 who underwent autologous PRP infusion after allograft bone transplantation were compared with 18 who underwent allograft bone transplantation only. Changes in pain and activities of daily living were assessed by a visual analog scale (VAS), the Harris Hip Score (HHS) and the time to bone fusion respectively, to evaluate differences between the two groups. Results: The VAS scores of patients who underwent autologous, PRP infusion was significantly improved compared to patients who did not undergo autologous, PRP infusion at post-operative 3 months(From 7.44 to 3.28 in PRP/ From 7.06 to 5.67 without PRP), but not at post-operative 12 months(From 7.44 to 6.95 / From 7.06 to 7.00). The HHS which showed no significant difference between groups(75 / 76). The mean time to bone fusion was 3.0 months (range, 1.5 to 5.7 months) in PRP group and 5.5 months (4.0 to 8.0 months) in without PRP group. Conclusion: Autologous, PRP infusion after allograft bone transplantation of core decompression for ONFH can promote bone fusion and initially produces effective pain control. However, the natural progression of disease, including femoral epiphyseal depression or osteonecrosis of the femoral head, is unlikely to be affected.
Authors and Affiliations
Baek S and Chung SH*
Keywords
Related Articles
- EP ID EP752095
- DOI -
- Views 20
- Downloads 0
Arthroscopic Sutures of the External and Internal Meniscus at Ordre De Malte Hospital in Dakar: The Case of 13 Patients
Introduction: The management of traumatic lesions of the menisci is an up to date topic. The treatment has for long remained mutilating and the evolution towards osteoarthritis inevitable. In the light of the original wo...
Monteggia Equivalents: Report of a New Variant of Type I- Salter Harris Type One Injury to Proximal Radius Physis and Olecronon Fracture
Introduction: Monteggia fracture dislocation in a child is relatively uncommon injury consisting approximately 1.5%–3% of the elbow injuries in the childhood. Case Presentation: A unique case of a type 1 Monteggia fractu...
Prognostic Factors of Cervical Cord Injury
Aim: Identify prognostic factors of management of cervical spinal cord injury in a low income country. Patients and method: This was a retrospective descriptive study which took place over 4 years and half, from 1st Janu...
Bilateral Ischiofemoral Impingement: A Case Report and Literature Review
Background: Ischiofemoral Impingement (IFI) is rare disease and more common in females than in males. It is characterized by hip and groin pain with abnormalities of the quadratus femoris muscle. The narrowing of ischiof...
Non Union of Fracture of the Neck of Femur in Young Adult
Non union is the most common complication of fracture neck of femur. Fracture of the neck of the femur has multiple factors leading to difficulties in union. Both biological and mechanical parameters contribute to the...