Clinical Features of Pseudotumour Cerebri Syndrome Syndrome: A Retrospective Evaluation of 60 Patients
Journal Title: Journal of Ankara University Faculty of Medicine - Year 2019, Vol 72, Issue 1
Abstract
Objectives: To evaluate the demographic, clinical and radiological characteristics of the patients who are followed up with the diagnosis of pseudotumour cerebri syndrome (PTCS). Materials and Methods: The etiological, symptomatic, ophtalmologic, radiological and treatment data of sixty cases that were followed up at the outpatient headache clinic between 2014 and 2018 were retrospectively analyzed. Results: Fifty-four female patients having an average age of (36.50±12.37) and 6 male patients having an average age of (33.70±9.17) were included in the study. Mean disease period was 8.91±12.73 months and mean body mass index value was 30.43±5.27. Etiologically, it was due to primary (73.3%) or secondary (26.7%) causes. Headache was present in 91.7% of the patients, tinnitus in 65%, diplopia in 16.7% and papiloedema was present in all the patients. In magnetic resonance imaging, extension of the perioptic subarachnoid space was observed in 26 patients, flattening in the posterior globe in 3 patients, Arnold-Chiari malformation in 1 patient, and empty sella in 9 patients. In the treatment, 43 patients used acetazolamide, 13 patients used acetazolamide and topiramate, 2 patients used acetazolamide, furosemide and topiramate, and 1 patient used topiramate. Optic nerve fenestration was applied to 1 patient. Conclusion: Update of the clinical and neuroimaging findings has brought a more detailed approach for the PTCS diagnosis. However, the pathophysiology of PTSS remains unclear. Researches on this regard will enable the development of more effective diagnosis and treatment methods.
Authors and Affiliations
Yasemin Eren
Keywords
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- EP ID EP48695
- DOI 10.4274/atfm.galenos.2019.80299
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