Clinical Outcome and Prognostic Factors for Nasopharyngeal Carcinoma: A Single Institution Study in Iran
Journal Title: International Journal of Cancer Management - Year 2017, Vol 10, Issue 3
Abstract
Background Evidence about survival of the patients with nasopharyngeal cancer is scant in our region and the aim of the current study was to determine clinico-pathological factors influencing outcome of these patients. Methods We reviewed all patients with a new diagnosis of nasopharyngeal carcinoma admitted between 2008 and 2014 to Jorjani cancer center, Tehran, Iran. Overall survival (OS) of the patients and their relation with demographic and clinico-pathological factors were analyzed. Results Of 88 included patients, 56 were male and 32 were female with mean age of 46 years. With a median follow-up period of 31 months (range: 3 to 86 months), the overall survival of the whole patients and those without distant metastasis were 64% and 67% respectively. Tumor stage and presence or absence of distant metastasis at presentation were the only parameters that significantly influenced the patients’ OS. Conclusions Our study provides some evidence on the outcome of Iranian patients with nasopharyngeal cancer and factors influencing it.
Authors and Affiliations
Ahmad Ameri, Nafiseh Mortazavi, Amir Shahram Yousefi Kashi, Kambiz Novin
Trends in the Incidence of Cancer in Iran (2003 - 2009)
Background Cancer is a leading cause of death throughout the world. Increasing life expectancy and aging population are important factors for increasing cancer incidences in devel...
The Molecular Mechanisms of Tobacco in Cancer Pathogenesis
Context: Studies have shown that cancer is a multi-factorial disease in its pathogenesis, in addition to genetic disorders, the effect of environmental factors can also be pointed. Among all environmental factors, tobacc...
Environmental Monitoring of Occupational Exposure to Cyclophosphamide Drug in Two Iranian Hospitals
Background: Most cytotoxic drugs are unable to discriminate normal cells from cancer cells and they interfere with cell division and could lead to harmful effects such as carcinogenicity, genetic mutation, and teratogeni...
Applying Bioinformatic Tools for Modeling and Modifying Type II <i>E. coli</i> l-Asparginase to Present a Better Therapeutic Agent/Drug for Acute Lymphoblastic Leukemia
Background Asparginase is known to be one of the most important bedrocks of acute lymphoblastic leukemia (ALL) treatment in almost all pediatric regimens in treatment protocols. <...
A Comparative Study of Treatment Toxicities Between FOLFOX 4 and Modified FOLFOX 6 in Iranian Colorectal Cancer Patients
Background: Colorectal cancer is one major health problem and cancer-related cause of death in cancer patients in countries such as Iran where the most cases are diagnosed in advanced stages. Objectives: To evaluate the...