Clinical profile and outcome of elderly patients with epilepsy in a Neurology tertiary care centre in Eastern India
Journal Title: Journal of the Indian Medical Association - Year 2017, Vol 115, Issue 12
Abstract
Elderly population (age 60 years or above), is the most rapidly growing population in the world and incidence of epilepsy is highest in the elderly. Epilepsy is an important health issue in this group. We conducted this study to identify characteristics and treatment outcome of epilepsy among elderly patients. We prospectively enrolled patients diagnosed with epilepsy with age of onset 60 years or older. Clinical data were collected and patients were followed-up for three months. Sixty six patients were included. Most frequent were focal seizures (72.72%), and localization related epilepsy was the most common type (n=57, 86.36%). Etiological diagnosis was possible in about 70% patients. Cerebrovascular disease (including hemorrhage and infarction) was the commonest cause of epilepsy. Interictal EEG showed epileptiform discharges in only 8 patients (12%). Most of the patients responded to monotherapy (80.3%). Levetiracetam (n=35, 53%) and Phenytoin (n=33, 50%) are the two most common AED taken by the patients. Most epilepsy in our population was focal onset mostly as a complication of cerebrovascular diseases. The overall effectiveness of AEDs treatment in elderly was satisfactory with most being stable on monotherapy.
Authors and Affiliations
Alak Pandit, Adreesh Mukherjee, Meghraj Singh Patel, Goutam Gangopadhyay, Biman Kanti Ray
Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a common disease with high global morbidity and mortality. COPD involves accelerated ageing of the lungs and an abnormal repair mechanism that might be driven by oxidative...
Short stature clinical approach to diagnosis : a 2018 perspective
Concern for linear growth or short stature is unequivocally the most common pediatric endocrine problem. Growth in children is complex and predictable at same time. It is easy to detect any deviation from normal growth i...
Awareness of Cancer Cervix and its prevention with HPV vaccine in internees, final MBBS students, Nursing staff and paramedical staff in a teaching institute
Aim of the study to collect information about the specific knowledge and awareness of CaCx and its seriousness & benefits of vaccination and screening. Konaseema Institute of Medical Sciences & Research Foundation (KIMS)...
Lipoprotein(a) : always relevant for Indians
Lipoprotein(a) [Lp(a)] comprises of an LDL-like particle consisting of apoB which is covalently bound by a disulfide bond to apolipoprotein(a) (apo[a]). Role of Lp(a) in promoting cardiovascular disease (CVD) is well-pro...
Review of transcatheter aortic valve replacement procedure in aortic valve stenosis
Severe symptomatic aortic stenosis is one of the commonest valve diseases due to various etiologies in elderly. Surgical aortic valve replacement (SAVR) was the treatment of choice in such cases. Transcatheter aortic val...