CLINICAL PROFILE OF ETHANOL-RELATED COMPLICATIONS IN AN ICU SETUP IN A TERTIARY HOSPITAL AT CHENNAI
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 51
Abstract
BACKGROUND Alcohol consumption is more common across subpopulations of South India. But the complications associated with alcohol consumption varies across the groups including those defined by age and gender of patient, amount, duration, brand of the alcohol used by the patient. Epidemiological survey conducted across world found that young adults (18 to 25) are at high risk of complications. With respect to gender, men reported more alcohol consumption and binge drinking than women. MATERIALS AND METHODS All patients with history of alcohol consumption admitted in ICU of Government Royapettah Hospital, Chennai were assessed and followed up from July 2016 to Feb 2017. The diagnosis was made based on the clinical presentation such as ascites, jaundice, upper GI bleed, hepatic encephalopathy, Wernicke’s encephalopathy with respect to age, sex, amount and duration of alcohol consumption. RESULTS Out of 52 patients in our study, 2 (3.8%) were female and remaining 50 (96.2%) were male. The higher incidence of complications was in the age group 40-59 yrs., which constituted 33 cases (63%), followed by 20-39 yrs. constituted 17 cases (33%). The least incidence was observed in the age group >60 yrs., 2 cases (4%). The incidence of complications observed in our study were symptomatic liver cirrhosis with minor complications (31%), upper GI bleeding (27%), hepatic encephalopathy (13%), Wernicke’s encephalopathy (13%), seizures (12%), hypoglycaemia (4%). CONCLUSION We observed that there is an increase in incidence of alcohol-related complications in younger age group. Acute complications without liver cirrhosis like UGI bleed due to erosive gastritis, Wernicke’s encephalopathy, seizures and hypoglycaemia were more with those who consumed large quantity of alcohol. Acute-on-chronic complications like UGI bleed secondary to liver cirrhosis and hepatic encephalopathy were directly proportional to duration of alcohol ingestion. In our study, we found that there is transition of acute alcohol-related complications from middle and older age group to younger age group. Hence, proper health education, legislation, early identification and treatment will decrease the morbidity and mortality due to acute alcohol-related complications.
Authors and Affiliations
Poongavanam Paranthaman, Ponnusamy Raja, Shaikh Sulaiman Meeran, Thenrajan Balaji, Abhijeet P. Lakhamawad
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