Clinical Profile of Haemophilia Patients at Govt. Royapettah Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Background Haemophilia group of related bleeding disorders that are inherited. Inherited bleeding disorders include abnormalities of coagulation factors and platelet function.Our country has the second highest burden of haemophilia patients in the world. Methods: This was an observational cross-sectional study .This study was done at Government Royapettah Hospital, Chennai for a period of six months. The study was performed after procuring informed written consent from all the participants involved. Results: The mean age of the study population was 25.28yrs.All the patients under the study were male.Of the study population of 50, only 8% knew the carrier status of their mother. The rest of the 92% were not aware of their maternal carrier status. In the group of 50 haemophiliacs, 30% had no family history. 20% were not aware of their grandfather’s or uncle’s disease status. 42% had a positive family history either in their maternal grandfather or maternal uncle.Of the study population80% were Haemophilia A and64% - Severe Haemophilia A, 16% had significant joint deformities. The rest of the 84% had normal range of movements.aPTT analysis showed an abnormal value (>40seconds) in about 48% of the study population..Analysis showed that the weight bearing joints – knees and ankles were most commonly affected. Right knee bleed contributed to 22% of the total bleeds in Haemophilia patients. Left knee contributed to 24% Conclusion: The severe type of haemophilia A was more common than mild and moderate types. The study suggest clinical profile of haemophiliac patients in our Government Royapettah hospital/KMCH
Authors and Affiliations
Dr. P. Paranthaman, Dr. S. Malathi
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