CLINICAL PROFILE OF NAFLD PATIENTS AND ITS CORRELATION WITH METABOLIC SYNDROME
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 4
Abstract
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is a clinico-pathological entity, increasingly recognised as a major health burden in developed countries and the fastest rising form of chronic liver disease worldwide. It is gaining concern among physicians in developing countries as well as it is predicted that its prevalence may surpass that of chronic hepatitis. It includes a spectrum of liver damage ranging from simple steatosis to non-alcoholic steatohepatitis (NASH), advanced fibrosis and rarely progression to cirrhosis. MATERIALS AND METHODS This was a descriptive study conducted in Department of Medicine, SSMC and SGMH, Rewa. A total of 200 cases were included in the study, who were diagnosed as having fatty liver on the basis of ultrasonography (USG) during the study period of April 2016 to July 2017 and were further investigated for metabolic syndrome. RESULTS Out of 200 cases, 55.5%, 36% and 8.5% of cases had grade I, II and III fatty liver respectively. 128 (64%) had metabolic syndrome. 63.93%, 61.11% and 76.84% of grade I, II and III NAFLD patients suffered from metabolic syndrome respectively. All the components of metabolic syndrome were significantly associated with NAFLD (p ≤ 0.05). CONCLUSION There is higher prevalence of all the components of metabolic syndrome in cases of NAFLD. Signs and symptoms are subtle and occur later in the course of the disease; hence, the physician should have a high index of suspicion in order to detect NAFLD early in the course of the disease. Early detection will help in modifying the disease course and delaying its complications.
Authors and Affiliations
Pradeep Nigam, Ravi Prakash Pandey, Meghna Pawar, Manoj Indurkar
Keywords
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- EP ID EP285816
- DOI 10.14260/jemds/2018/96
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