CLINICAL PROFILE OF OPTIC NEUROPATHY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 24
Abstract
BACKGROUND Optic neuropathy is a frequent cause of vision loss encountered in clinical practice. It is important to diagnose and treat the condition in a timely manner to prevent visual disability. The diagnosis is made primarily on clinical grounds. A rapid onset is typical of demyelinating, inflammatory, ischaemic and traumatic causes. A gradual course points to compressive, toxic/ nutritional and hereditary causes. The aim of this study was to evaluate the clinical profile of Optic Neuropathy. MATERIALS AND METHODS All patients presenting to Osmania General Hospital with visual loss and those referred from Sarojini Devi Eye Hospital with optic neuropathy were included in the study. All these patients had already undergone ophthalmic examination, detailed clinical history, complete neurological examination, imaging and special investigations as required. RESULTS The highest incidence of optic neuropathies was seen in the age group of 21 - 30 years with female preponderance, presentations were unilateral bilateral simultaneously and sequentially. Painful vision loss was seen in 42% of cases. RAPD was seen in 21 patients on the whole in our study. Disc oedema and blurring with or without haemorrhages were seen in 19 (38%) patients. Most patients had an abnormal VEP in the form of either a delayed P100 or a reduced amplitude. The CSF proteins were increased in 22% of the patients and Oligoclonal bands were seen in 5 patients. Demyelination is the most common cause followed by ischaemia and other causes. CONCLUSION Optic neuritis was found to be the commonest cause of optic neuropathy in this study. A detailed clinical examination especially fundoscopy, imaging, CSF analysis are required to arrive at aetiology of optic neuropathy.
Authors and Affiliations
Ramesh Ramachandra, Deepthi Kiran, Kirthitheja Bommakanti, Nikhil Goli
Keywords
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- EP ID EP450596
- DOI 10.14260/jemds/2018/649
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