Clinical Utility of Different Lipid Measures in Acute Coronary Syndrome in Young: An Observational Study in North Kerala
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 5
Abstract
Lipoprotein (a) is an emerging independent and compounding risk factor for the development of CAD (coronary artery disease. The present study was done to assess the fasting lipid profile, fasting Apo B-ApoA1 ratio and Lipoprotein (a) levels in patients with acute coronary and to evaluate whether these parameters predicts the risk of developing acute coronary syndrome in young subjects. Patients and Methods The present observational study was carried out in patients with first episode acute coronary syndrome, presented in Calicut Medical College during the study period.All patients were evaluated with baseline investigations like ECG, fasting blood sugar, fasting lipid profile- {total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides total cholesterol –HDLratio}, fasting apoB-apoA1 ratio, & lipoprotein (a).cardiac enzyme makers and echocardiography in indicated cases. Results This study clearly proves the role of hypertension, diabetes mellitus, obesity, family history of hypertension, diabetes and acute coronary syndrome. Metabolic syndrome is very prevalent in South Asians and should be screened for accordingly. Waist-hip ratio or waist circumference rather than BMI should be used to screen for central obesity. Smokers have a high risk of developing ACS, but association of alcohol consumption and ACS is not statistically significant. Emerging risk factors such as apoB-apoA1 ratio.Lp(a)_ are significant risk markers of acute coronary syndrome. But this study suggest that replacement of traditional lipid values with apoB-apoA1 ratio, Lp(a) adds little to risk assessment in acute coronary syndrome. Conclusion Thus the study exemplifies that, in the present study, patients belong to poor economic status, total cholesterol – HDL ratio is as efficient, as the emerging risk factors, included in this study.
Authors and Affiliations
Dr. Kamalasanan
Keywords
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