Clinico-demographic Profile and coinfections among hospitalized children with chikungunya in a tertiary care hospital of North India: lessons learnt
Journal Title: Indian Journal of Child Health - Year 2018, Vol 5, Issue 9
Abstract
Background: Chikungunya is a vector-borne arboviral disease. Children are known to have atypical manifestations. Overlapping features with other infections can make the diagnosis difficult. Objective: The objective was to study the clinicodemographic and laboratory profile of chikungunya and the impact of coinfections on the course and outcome among hospitalized children. We conducted the study during a large outbreak of chikungunya in the national capital. Materials and Methods: A retrospective analytical study was conducted on children admitted from July to November 2016 at a tertiary care hospital in North India. Case records of all hospitalized children (1 month–14 years) with immunoglobulin M positive chikungunya serology were reviewed. Children were categorized into Group A (isolated chikungunya infection) or Group B (coinfection) after entering baseline data, clinical, laboratory, and management details in a pre-designed case record pro forma. Groups A and B were compared to see any statistically significant difference in the clinical and laboratory parameters using appropriate statistical tests. Results: Of 102 children, 45 (44.1%) had isolated chikungunya and 57 (55.9%) had chikungunya with other coinfections. In the coinfection group, 37 (36.3%) had dengue, 7 (6.8%) enteric, 6 (5.9%) malaria, 5 (4.9%) pyomeningitis, and 2 (2%) viral hepatitis-A. Vomiting and splenomegaly (p<0.05) were significantly more in the coinfection group. The classic triad of chikungunya was present in only three cases of isolated chikungunya. Conclusion: Children lack the classical triad of chikungunya and coinfections are very common in children.
Authors and Affiliations
Shivani Deswal, Ajeet Kumar Yadav, Soumya Dey, Tribhuvan Pal Yadav, Chander Prakash Yadav
Keywords
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