Clinico-Epidemiological Profile of Pemphigus: An Observational Study
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 8
Abstract
Background: Pemphigus is a group of rare, chronic, autoimmune, potentially fatal vesiculobullous diseases of the mucous membranes and skin. Clinical profile and epidemiologic characteristics varies in different parts of the world. Aim: The aim of this study was to evaluate the clinical and epidemiological features of pemphigus in our hospital and to compare the results with those in the literature. Methods: All newly registered patients with confirmed pemphigus admitted at the Department of Dermatology between the period August 2009 and July 2015 were evaluated. Demographic variables and clinical presentation, treatments received were recorded. Results: Out of 91 patients diagnosed as pemphigus in our centre during the period of 6 years pemphigus vulgaris was the most common type (91.2 %). The mean age of onset was 45 years. Male to female ratio in the patients with pemphigus vulgaris was 1: 1.5. Oral lesions were found in 84 % of patients and it was the first manifestation in 66%. Mortality rate was 1% (2 cases) which was due to sepsis. There was no mucosal involvement in patients with pemphigus foliaceus. Only 1 patient had a positive family history. No seasonal predominance for the onset of the disease was noted. Conclusion: Pemphius vulgaris is the predominant form of pemphigus seen followed by pemphigus foliaceus. Oral mucosa as well as skin are the major sites of involvement. Due to increase in life expentancy occurance of Pemphigis is not an uncommon condition in elderly individuals.
Authors and Affiliations
Anand J Asia
Keywords
Related Articles
- EP ID EP212270
- DOI -
- Views 70
- Downloads 0
Biochemical Parameters in Acute Myocardial Infarction with or Without Co-Morbidities
Acute myocardial infarction is one of the most common cause of death and one of the most frequent causes of hospitalization. Acute Myocardial Infarction occurs when there is an imbalance between supply and demand for oxy...
Influence of Immediate and Long Term Effects of Repetitive Transcranial Magnetic Stimulation Combined with Speech Therapy on Post Stroke Nonfluent
Background: A high proportion of patients who have suffered a stroke also suffer from aphasia. The aim of this work was to determine and investigate immediate and long term effects of repetitive transcranial magnetic sti...
Propofol or Sevoflurane for Laryngeal Mask Airway Insertion-A Comparative Study
Induction agents were proposed. This study attempts to compare effects of propofol and sevoflurane with the help of an accepted scoring system. We conducted this prospective study at SAT hospital government medical colle...
The Role of Presepsin, C-Reactive Protein and Procalcitonin as a Marker of Therapy Response and Prognosis for Late Onset Neonatal Sepsis in Preterm Neonates
Introduction: C-reactive protein (CRP) and procalcitonin (PCT) are the most widely used diagnostic and monitoring markers of neonatal sepsis. There is currently a new sepsis marker, Soluble CD14 subtype (sCD14-ST) presep...
Throbocytopenia an Indicator of Malaria in Febrile Patients- A Retrospective Study
Back ground: Malaria is a major health problem in India. It is mosquitoe born protozoal disease caused by parasite of the genus Plasmodium. Various hematological consequences are produced in patients with this infection,...