Clinico-Morphological Profile of Adrenal Tumors in Childhood
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
The clinical manifestations and biologic behaviour of adrenal tumors in childhood can be quite distinct from their histologically similar counterparts in the adult population. We report 5 cases of adrenal neoplasms in young children and review their clinical presentations, endocrinological profile, pathology, and follow-up data. Pathologic evaluations included histology and immunostaining with NSE, synaptophysin and chromogranin. The patients included 3 girls and 2 boys, all <11 years of age. All the patients presented with hormone-related symptoms like Cushing syndrome for an average duration of 6 months. Serum testosterone levels were elevated in 2 cases. Imaging studies revealed neoplasms in the left adrenal gland in 2 cases and in the right adrenal gland in 3 cases. No evidence of disease was identified at any other site of the body. The tumors were grossly confined to the adrenal glands and ranged in size from 1.5 to 4.8 cm diameter. Microscopically, the tumors had histological and immunohistochemical features characteristic of adrenocortical tumors and neuroblastomas.
Authors and Affiliations
Pranati Pradhan, Pragyan Lisha Panda
Keywords
Related Articles
- EP ID EP530057
- DOI 10.21276/ijmrp.2018.4.1.061
- Views 82
- Downloads 0
Clinical Analysis of Spinal Tumours at a Tertiary Care Center
Background: Tumours of the spinal cord have long been a welcome entity for the neurosurgeons because in contrast to the brain tumour, they are in majority benign, circumscribed & surgically accessible. The post-operative...
Clinicopathological Pattern of Anemia in Children in Age Group Upto 18 Year
Introduction: Anemia is a nutritional problem of Global importance. It is estimated that at least one-third of the population has been at one time anemic. Objective: To evaluate the prevalence of anemia in patients admit...
A Prospective Study to Assess the Prevalence of Osteoporosis in COPD Patients Based on Dual Energy X-Ray Absorptiometry (DXA)
Background: Chronic obstructive pulmonary disease (COPD) is a condition observed by a gradual airflow limitation that is not fully reversible and an inflammatory response of the lung to noxious particles and gases is obs...
Role of Two Stage Urethroplasty in Modern Era with Special Reference to Impact on Sexual Health Function
Introduction: Urethral stricture is a prevalent problem throughout the globe. However, with improvement in surgical skill there is a shift towards single stage repair with substitution urethroplasty for long strictures....
A Study on the Prevalence of Allergic Skin Disorders among Students Of Majma'ah University, Majmaah, Saudi Arabia
Introduction: Allergic disorders are a group of immune-mediated disorders that are associated with considerable morbidity and ill health. Allergies affecting students in their college years greatly affects the quality of...