Clinicopathological Profile of Hodgkin Lymphoma in Tertiary Care Hospital
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Abstract: Hodgkin lymphoma is one of the most enigmatic diseases known. Our aim is to study the epidemiology of Hodgkin lymphoma including age and sex incidence and to highlight the differences in the clinical and pathological profile of Indian Hodgkin lymphoma from its western counterparts. Materials and methods: A total of 142 cases were studied. The case records were reviewed for clinical presentation. The H&E slides were studied to assess the morphology, presence of Reed Sternberg cells and its variants and background infiltrate. Results: There was a bimodal age distribution noted. The age range was 9-77 years. The Male: female ratio was 1.77:1. Classical Hodgkin Lymphoma is the most common type (93%) with mixed cellularity be the predominant subtype. Stage II disease was predominantly seen. Conclusion: Our study highlights the differences in the clinical and pathological profile of Indian Hodgkin lymphoma from its western counterparts. Mixed cellularity was the most common subtype in contrast to western population in which nodular sclerosis is common. Distinct pattern of expression of Hodgkin lymphoma was noticed which is comparable to some of the Indian studies and different from other western studies.
Authors and Affiliations
DR. P. Geetha M. D. , Prof DR. Geetha Devadas M. D.
Keywords
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- EP ID EP593022
- DOI 10.9790/0853-1603032326
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