Clinicopathological Spectrum Of Non Adenocarcinomatous Tumors Of Pancre As Benign As Well As Malignant
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 3
Abstract
Background:Although adenocarcinomas are the most common tumors of pancreas the incidence of non adenocarcinomatous tumors e.g. neuroendocrine neoplasms, solid pseudopapillary neoplasms is rising partly due to advancement in diagnostic methods. AIMS and Objectives :To study the histopathological patterns of non adenocarcinomatous tumours of pancreas (Benign as well as Malignant) and to study the clinical profile of the patients related to age, gender, symptoms, radiological findings. Subjects and Methods:The study was conducted at Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir in the department of Pathology. It was a prospective study for a period of one and a half years(1.5 yrs) from July 2013 to December 2014 and retrospective for a period of 19 years from July 1994 to June 2013.The study included all the cases of non adenocarcinomatous tumors of pancreas (benign as well as malignant) . Results:Well differentiated neuroendocrine carcinoma was the most common single neoplasm accounting for 34.14% of the cases. Second most frequent neoplasm was mucinous cystadenoma comprising 19.51% of the cases. Serous cystadenomas were the third most frequent neoplasms constituting 17.07% of the cases. Four (9.75%) cases of solid pseudopapillary neoplasms were seen. Two (4.87%) well differentiated neuroendocrine tumors were seen. One case each of cavernous hemangioma, lymphangioma, intraductal papillary mucinous neoplasm with invasion, without invasion, gastrointestinal stromal tumor and pancreatic intraepithelial neoplasia was seen. There was a strong female predominance with 76% of the cases seen in females. Conclusion: Most of the cases in our study have been diagnosed in the last decade only which clearly shows that improvement in diagnostic modalities and knowledge about these tumors have helped in diagnosing more of these tumours correctly and early.
Authors and Affiliations
Danish Rafiq, Mir Wajahat- un- Nazir, Tazeen jeelani, Yaavar shafi
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