Clinicopathological Spectrum of Pancytopenia in Tertiary Care Centre in Northern India
Journal Title: RECENT ADVANCES IN PATHOLOGY AND LABORATORY MEDICINE - Year 2018, Vol 4, Issue 3
Abstract
Introduction: The term pancytopenia refers to a reduction in all three formed elements of blood-erythrocytes, leucocytes and platelets. It is not a disease entity, but rather a triad of findings that may result from a number of disease processes. The causes of pancytopenia vary depending on multiple factors. This prospective study was conducted to find out various causes of pancytopenia and their relative frequencies in a tertiary care hospital in northern India. Methods: In the present study, 60 cases were taken up for a period of 2 years at a tertiary care hospital in Northern India. The study was composed of a brief work up of history, general and systemic examination and complete hematological work up. All the data was compiled and a final diagnosis was made. Results: The age of the patients varied from 6 months to 70 years consisting of 34 males (57%) and 26 females (43%). Megaloblastic anemia was the most common cause (66.7%) followed by aplastic anemia (19%) and malignancies (6.7%). Infections and parasitic infestations accounted for the rest. Conclusion: In our study, more than 50% of the cases are due to megaloblastic anemia prevalent due to dietary deficiency & malnutrition. Also, infections and infestations (Tuberculosis, malaria, kalaazar and typhoid) should be kept in mind as a differential diagnosis of pancytopenia.
Authors and Affiliations
Dr. Karsing Patiri
Keywords
Related Articles
- EP ID EP396580
- DOI 10.24321/2454.8642.201810
- Views 59
- Downloads 0
Squash Smear Technique in Rapid Intraoperative Diagnosis of Brain Tumors
The role of rapid intraoperative diagnosis is crucial to neurosurgeons to not only define surgical approach, but also to ensure that minimum injury is caused to normal structures surrounding the lesion. Intraoperative cy...
A Study to Correlate Endometrial Hyperplasia with Ovarian Stromal Change
Background: Endometrial hyperplasia in peri-menopausal age group is frequently encountered as a result of unopposed excess estrogen action, exact source of which is still debatable. Possible source is ovarian stroma. The...
Diagnostic Accuracy of USG-Guided FNAC in Gall Bladder Mass
Introduction: Malignancy of gall bladder is quite common. However, it cannot always be diagnosed only by clinical history and examination. We have evaluated diagnostic accuracy of USG-guided FNAC in GB mass.
Histomorphological Spectrum of Head and Neck Lesions: A Three Year Retrospective Analysis
Background: Lesions of head and neck are common in patients of all age groups. Head and neck cancers including thyroid lesions are the third commonest malignancy seen in both sexes across the globe. Aim: To study the his...
Recurrent Malignant Phyllodes Tumor of the Breast: A Rare Occurrence in a Young Nulliparous Woman
Phyllodes tumor of the breast is an uncommon fibroepithelial neoplasm and accounts for less than 1% of the primary breast neoplasms. The median age of its occurrence is 40–50 years. It has been sub-classified histologica...