Co-Existence of Scleroderma and Tuberculosis
Journal Title: Scholars Journal of Medical Case Reports - Year 2015, Vol 3, Issue 1
Abstract
Scleroderma is a chronic systemic autoimmune disease characterized by fibrosis, vascular alterations, and autoantibodies. This causes widespread symmetrical thickening of the skin followed by atrophy and pigmentation. Patients with immune-mediated diseases are known to have an increased risk of Tuberculosis. Mycobacterial infections are also known to induce the development of autoantibodies. We report a case presented with clinical features of pulmonary tuberculosis with general examination and radiological findings raising the suspicion of a co-existent connective tissue disorder. Antibody profile done and was found to be positive for ANA and anti-Scl-70 thus confirming the diagnosis of scleroderma coexisting with Pulmonary Tuberculosis. Hence here by we highlight the importance of suspicion, careful general examination, radiological assessment and screening tuberculosis patients for autoantibody profile in presence of a multisystem involvement.
Authors and Affiliations
Subramanian S, Ragulan. R, Natraj. M, Meenakshi. N, Viswambhar. V
Keywords
Related Articles
- EP ID EP375243
- DOI -
- Views 61
- Downloads 0
Variations of Musculocutaneous Nerve- A Case Report
Musculocutaneous nerve (MCN) arises from the lateral cord (C5-C7)of the brachial plexus. It is the nerve of the anterior compartment of arm. The median nerve (MN) has two roots from the medial (C8,T1)and lateral (C5,C6,C...
Granulomatosis of Wegener: Revealed by a Total Necrosis of the Nasal Pyramid
The granulomatosis of Wegener is a necrotizing, rare systematic vasculitis, of a not yet established origin. It must be evoked in front of a clinical set of three, dominated by the ENT signs, a total necrosis of the nasa...
An Unusual Case of Tubercular Recto-Prostatic Urethral Fistula
Rectourethral fistula is an uncommon occurrence. The usual anatomic site of occurrence is the prostatic urethra,in which a communication develops with the rectum. The common causes are surgery or radiotherapy for prostat...
Unusual Case of Rhinoscleroma: A case report
Rhinoscleroma is a progressive chronic granulomatous disease of the respiratory tract. Itusually involves the nose but can rarely progress to involve the nasopharynx , oropharynx , larynx, trachea and bronchi. We...
Phlegmasia Cerulea Dolens in a Patient with Newly Diagnosed Rheumatic Disorder
Phlegmasia cerulea dolens (PCD) is a rare and critical complication of deep vein thrombosis (DVT) that results from extensive thrombotic occlusion of the major and collateral veins of an extremity, which back up into the...