Co-Relation between Vitamin D Levels and Hamilton Depression Scores in Patients with Depression
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 7
Abstract
Mood disorders have been described as one of the most common illnesses of humankind for last 2500 years. The vitamin D receptors are present on various areas of the human brain. There are various biological mechanisms that may explain the relationship between vitamin D deficiency and the risk of depression. The vitamin D receptors are present on various areas of the human brain (ie. prefrontal cortex, hippocampus, cingulated gyrus, thalamus, hypothalamus, and substantia nigra), that are important in pathophysiology of depression. 50 cases of major depression were randomly selected from psychiatry OPD and an equal number of controls with matched age, sex, religion and socioeconomic background were also recruited for the study. Hamilton Depression rating was done and their Vitamin D level was checked. It was found that Severity of depression has indirect relationship with vitamin D levels in depressed patients.
Authors and Affiliations
Dr Gaurav Sharma
Keywords
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