Cognitive impairment in patients with type 2 diabetes mellitus: the role of hypoglycemic therapy

Abstract

The article presents data on epidemiology, risk factors, mechanisms of development, clinical features of cognitive impairment in patients with type 2 diabetes mellitus. The literature data about the dependence of the incidence and severity of cognitive impairment on the type of hypoglycemic therapy are analyzed. As well as the results of clinical and experimental studies concerning the peculiarities of cognitive functions against the background of using various antidiabetic agents — meglitinides, biguanides, thiazolidinediones, glucagon-like peptide-1 receptor agonists, dipeptidyl peptidase-4 inhibitors, sodium-dependent glucose cotransporter 2 inhibitors and insulin.

Authors and Affiliations

N. V. Pashkovska

Keywords

Related Articles

Impact of Vitamin D Supplementation on the Level of Thyroid Peroxidase Antibodies in Patients with Autoimmune Hypothyroidism

In spite of studying the relationship between the deficiency and the lack of vitamin D in autoimmune thyroid disorders, the effect of additional administration of the preparations of this vitamin has not been clear in su...

Peculiarities of biochemical blood parameters and cytokine profile in patients with non-alcoholic fatty liver disease depending on the form of hypothyroidism

Background. The purpose of the study was to investigate the biochemical blood peculiarities and cytokine profile in non-alcoholic fatty liver disease (NAFLD) patients depending on the form of hypothyroidism. Material and...

The rs1800629 polymorphism of the TNFα gene in type 2 diabetes mellitus: association with nephropathy

Background. In diabetes mellitus (DM), endothelial dysfunction (EDF) is formed that determines the rate and severity of the disease complications. Among other factors, there is the presence of genetic polymorphism, which...

New guidelines of the American Diabetes Association 2018 on the diagnosis and treatment of diabetes mellitus

The article considers some aspects of the recently published recommendations of the American Diabetes Association on the diagnosis, prevention and treatment of diabetes mellitus.

Genetic Determinism of the Functional Condition of the Endothelium in Patients with Chronic Diffuse Liver Diseases and Disorders of Thyroid Homeostasis

Patients with chronic diffuse of liver disease have a violation of thyroid homeostasis in the form of reduction of free triiodothyronine in the blood serum, as well as thyroid stimulating hormone increasing content and o...

Download PDF file
  • EP ID EP275725
  • DOI 10.22141/2224-0721.14.1.2018.127097
  • Views 72
  • Downloads 0

How To Cite

N. V. Pashkovska (2018). Cognitive impairment in patients with type 2 diabetes mellitus: the role of hypoglycemic therapy. Міжнародний ендокринологічний журнал, 14(1), 76-85. https://europub.co.uk./articles/-A-275725