COLD PRESSOR TEST IN NORMOTENSIVE AND GRADE – I ESSENTIAL HYPERTENSIVE PATIENTS
Journal Title: Indian journal of applied basic medical sciences - Year 2018, Vol 20, Issue 30
Abstract
Background: Hypertension is creating not only health problems but also economical burden on working population in India. Autonomic nervous system (ANS) via its sympathetic and parasympathetic limbs plays a crucial role in maintaining the blood pressure (BP). Generally hypertensive population reacts differently as compared to normotensive to various forms of the stress.Aims and Objective: Present study was carried out to assess the role of ANS, specifically sympathetic nervous system in cardiovascular hemodynamics in Grade-I essential hypertensive subjects compared to normotensive along with the gender variation.Materials and Methods: Study included 80 volunteers of age 35 to 50 years, 40 normotensive subjects (20 Male and 20 Female) forms control group and 40 diagnosed Grade–I essential hypertensive (20 Male and 20 Female) forms study group. Systolic and diastolic BP of participants was measured at rest, at 30 and 60 seconds intervals during cold pressor test and at 1 minute interval till BP returns to resting value or at least 5 mm of Hg less than resting systolic BP after the cold pressor test. Then difference between rise in systolic and diastolic BP and resting BP was calculated and compared between control and study group’s males and females.Statistical analysis:Student‘s unpaired ‘t’ test was appliedand outcomes were presented as mean (SD).The ‘p’ value < 0.05 was considered as significant and < 0.001 as highly significant.Results:Study found highly significant rise in systolic and significant rise in diastolic BP of hypertensive male where as only significant rise in systolic BP of hypertensive females compared to normotensive group. In females, the rise of diastolic BP was more but it was not statistically significant. Recovery towards basal level was also slow in hypertensive male and female subjects. Conclusion: There is definite cardiovascular ANS dysfunction, specificallysympathetic in Grade–I essential hypertensive patients. More research work is needed to obtain precise relationship between ANS and hyper responsive response to stress in hypertensive patientsas regulation of BP has multiple components.
Authors and Affiliations
Lalita M, Gulhane Sonali
Keywords
Related Articles
- EP ID EP267015
- DOI -
- Views 123
- Downloads 0
(4) DOES THE NUMBER OF CIGARETTES SMOKED PER DAY AFFECT THE AGE OF ONSET OF ACUTE MYOCARDIAL INFARCTION AND SERUM TOTAL CHOLESTEROL?
ABSTRACT INTRODUCTION : The habit of Smoking is uniquely human and is indulged in almost all over the world in different forms. It is done solely for personal pleasure and satisfaction. Tobacco is smoked by people in var...
14 Non operative vs operative management of blunt hepatic injury A Retrospective Study Dr Shaishav V Patel
Back ground:The liver is one of the most frequently damaged organs and remains the most common cause of death following blunt abdominal trauma. During the last century, the management of blunt force trauma to the liver h...
21 VISUAL OUTCOME IN METHANOL POISONING A STUDY OF AN OUTBREAK IN AHMEDABAD IN JULY 2009 ,
is paper describes various aspects of presentation of methyl alcohol poisoning, especially ophthalmic and its correlation with visual outcome with different modalities of management. In the outbreak of methyl alcohol poi...
24 A STUDY OF COMPARISON BETWEEN SILK LIGATION AND BIPOLAR CAUTERY IN TONSILLECTOMY
Background: Tonsillectomy is one of the most commonly performed surgical procedure. Different techniques and instruments have been used for removal of tonsils along with haemostasis but none of them were found satisfacto...
5 A STUDY ON RELATION OF SUBCLINICAL HYPOTHYROIDISM DURING PREGNANCY WITH ITS OUTCOMES IN GUJARAT.
INTRODUCTION:Pregnancy is a period that places great physiological stress on both the mother and the fetus. When pregnancy compounded by endocrine disorders such as hypothyroidism, the potential for maternal and fetal ad...