Colonoscopy-assisted Fecal Microbiota Transplant for Outpatient Treatment of Recurrent or Refractory Clostridium Difficile Colitis; Long Term Follow-up of 58 Patients
Journal Title: Journal of Clinical Gastroenterology and Treatment - Year 2016, Vol 2, Issue 1
Abstract
Clostridium difficile infection (CDI) costs the national healthcare system billions of dollars annually, and is reaching epidemic proportions. The current study seeks to evaluate the efficacy and long term outcomes of outpatient colonoscopy-assisted fecal microbiota transplant (FMT) therapy in between 2011-2013 for recurrent or refractory CDI as part of a single center experience. Among 58 patients who underwent FMT and completed the telephone survey, 91.4% were disease free at the 3 month interval, 86.2% at the 6 and 12 month intervals, and 80.5% at the 18 month interval post FMT. Purpose: The current study seeks to evaluate the efficacy and long term outcomes of outpatient colonoscopy-assisted fecal microbiota transplant (FMT) therapy in between 2011-2013 for recurrent or refractory CDI as part of a single center experience.
Advances and Controversies in the Management of Locally Advanced Gastro-esophageal Adenocarcinoma
Esophageal adenocarcinoma (EAD) has been recently described as ‘the silent epidemic’ because of its rapidly rising incidence. Two-thirds of patients with esophageal adenocarcinoma present with locally advanced disease. I...
"Colonic Lipoma: Incidental and Urgent Management, Report of Two Cases and Review of the Literature"
Lipomas are benign tumors rarely found in the digestive tract, particularly rare in the colon, that were first described by Bauer in 1757 as an unusual cause of intussusception in the adult. Lipomas are most often small,...
MMPs, ADAMs and Their Natural Inhibitors in Inflammatory Bowel Disease: Involvement of Oxidative Stress
Matrix metalloproteinases (MMPs) are enzymes involved in the degradation of extracellular matrix proteins and in several functions such as wound repair. The regulation of MMPs occurs at various levels including expressio...
A Case of Serial Liver Injury Induced by Plant Food Supplements in a Young Healthy Man
The use of botanicals is increasingly throughout the world. They are ingredients of different types of products, such as herbal medicinal products, Plant Food Supplements (PFS), and functional foods. They are commonly ta...
Validation of a Simple, Patient Directed, Symptom based Index for Intestinal Inflammation
Objective: Optimal management of the Inflammatory Bowel Diseases (IBD) aims for low levels of inflammation to reduce complication rates and disease burden. Scoring systems have been developed to monitor disease but most...