Combined spinal epidural for labor analgesia comparison of two different doses of intrathecal bupivacaine 1.25 mg and fentanyl 25 µg with bupivacaine 2.5 mg and fentanyl 25 µg
Journal Title: Asian Pacific Journal of Health Sciences - Year 2018, Vol 5, Issue 2
Abstract
Background and Objective: The responsibility of the anesthetist in obstetrics is very high. This study compares two different low doses of intrathecal bupivacaine 1.25 mg and 2.5 mg along with 25 µg fentanyl as the spinal component of combined spinal epidural (CSE) analgesia in the early part of labor, followed by epidural top-up. Methodology: Approval was obtained from the institutional review board and written informed consent was obtained from 60 healthy term primigravida or the second gravid parturients, with cephalic singleton pregnancy between 36 and 42 weeks, ASA Grade I/II patients. The study was conducted using low-dose intrathecal bupivacaine 1.25 mg and fentanyl 25 µg (GroupI) with bupivacaine 2.5 mg and fentanyl 25 µg (Group II) as the spinal component of CSE analgesia in the early part of labor. We compared the two with respect to their onset, duration of sensory and motor block, quality of analgesia during early part of labor and the side effects of the drugs. Results: The onset of analgesia was equally rapid with both groups within 5 min, lower incidence of motor block with Group I compared to Group II. Duration of analgesia was longer in Group II, associated with higher dermatome levels of sensory block with longer time for regression of the block. Conclusion: We found that bupivacaine 1.25 mg was as effective as bupivacaine 2.5 mg when added to fentanyl 25 µg for CSE.
Authors and Affiliations
Gunjan Agrawal
Keywords
Related Articles
- EP ID EP521605
- DOI 10.21276/apjhs.2018.5.2.13
- Views 167
- Downloads 0
Experience of sexual/reproductive health and dance education in a care and social rehabilitation center
Purpose: In the study, a dance training was made in order to encourage personality development and information about Sexual Health/Reproductive Health (SH/RH) was given in order to raise awareness and precision to adoles...
Immunization Perception and Awareness among Mothers Attending OPD of a Tertiary Care Hospital of Karachi, Pakistan
Background: Immunization plays tremendous role in significant reduction of childhood morbidity and mortality. For this, the World Health Organization introduced EPI. Unfortunately, this goal is not achieved yet. This stu...
An analysis of frontal extradural hematoma and its radiographic features
Background: The extradural hematoma is the most important expanding lesion due to head injury with high indexes of mortality and morbidity when the correct management is not done. Frontal extradural hematoma (FEH) is con...
Outcome of dacryocystectomy with nasal bone osteotomy for lost nasal flap dacryocystorhinostomy with repeated post-operative probing
Aim: (1) To evaluate the effect of dacryocystectomy (DCT) with osteotomy on correction of epiphora in terms of subjective and objective assessment and (2) to compare the outcome of probing with non-probing in DCT with os...
A study on C-reactive protein as an early marker of vasococclusive crisis in sickle disorders
Background: Sickle cell disease (SCD) patients often seek care in the Emergency Department (ED) due to vaso-occlusive crisis (VOC), the most common complication of SCD. Currently, no diagnostic test can determine if a SC...