COMPARATIVE ANALYSIS OF PATHOGENS OF VIBRIOSES ISOLATED IN UKRAINE
Journal Title: Наукові доповіді НУБіП України - Year 2017, Vol 2, Issue 2
Abstract
Strains of V.cholerae O1 and V.cholerae non O1 with various pathogenic potential for diseases from acute enteric infections (AEI) to cholera are isolated from people in Ukraine every year. Studies of biological properties of Vibrio choleraе O1 strains showed variability in their characteristics manifested in loss of sensitivity to diagnostic cholera antisera and phages, which complicates identification and finding virulence determinants. Virulent strains of V.cholerae O1 are mainly isolated from people during cholera outbreaks, while avirulent variants are found in periods between outbreaks. There are atypical strains of V.cholerae non O1 which can agglutinate with cholera antisera and lysed by cholera phages. There is biological variability in antigenic structure and lysability by phages. Circulation of V.cholerae O1/non O1 with different biological properties in Ukraine needs to be constantly monitored for changes in their properties using more informative study methods to ensure prompt response in case of the escalation of epidemiological situation in the country.
Authors and Affiliations
О. V. P Petrenko, V. V. Аlekseenko
Keywords
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