COMPARATIVE ANALYSIS OF POLYMORPHISM OF THE CFTR GENE IN UZBEK POPULATION
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 1
Abstract
One of the factors of male infertility is cystic fibrosis. This is a monogenic autosomal recessive disease caused by a mutation of the cystic fibrosis transmembrane conduction regulator gene, characterized by lesions of the exocrine glands of vital organs and usually with a severe course and prognosis. The severity of the disease and symptoms may vary depending on the type of mutation. Different mutations and polymorphisms of the CFTR gene have a pronounced population specificity, reflecting the genetic processes that are emerging.
Authors and Affiliations
Fayzullaeva Nigora Yakhyayevna
Keywords
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