Comparative Anti-oxidant Activity of Aqueous and Organic Extracts from Kenyan Ruellia lineari-bracteolata and Ruellia bignoniiflora
Journal Title: European Journal of Medicinal Plants - Year 2016, Vol 17, Issue 1
Abstract
Medicinal plants play a significant role in treatment and prevention of many diseases in humans worldwide. Ruellia species belong to the family Acanthaceae and have been used widely for medicinal purposes. The objective of this study was to evaluate the comparative In vitro anti-oxidant activity of two Kenyan Ruellia species viz. Ruellia lineari-bracteolata (RLB) and Ruellia bignoniiflora (RBK). The plant materials were extracted with aqueous, ethyl acetate and methanol. The extracts were subjected to phytochemical screening according to standard procedures and anti-oxidant activity determined using 2, 2-Diphenyl-1-picrylhydrazyl (DPPH) assay. Comparative anti-oxidant activity for methanolic, ethyl acetate and aqueous extracts of RLB and RBK exhibited IC50 values of (2.7, 29.3, 7.2 and 24.4, 237.2, 66.4 μg/ml) respectively. Among the three extracts, methanolic extract showed better activity (2.7 μg/ml) comparable to ascorbic standard (2.1 μg/ml). Between the two Ruellia species, RLB showed a significant difference (p<0.05) in anti-oxidant activity as compared to RBK extracts. Phytochemical screening showed the presence of terpenoids, saponins, flavonoids, tannins and glycosides. Flavonoids and tannins are the main phytoconstituents responsible for anti-oxidant activity. In conclusion, the potent anti-oxidant activity of these plants makes them useful in development of medicinal drugs for treatment and prevention of degenerative diseases.
Authors and Affiliations
Christine O. Wangia, Jennifer A. Orwa, Francis W. Muregi, Patrick G. Kareru, Kipyegon Cheruiyot, Japheth Kibet
Keywords
Related Articles
- EP ID EP349621
- DOI 10.9734/EJMP/2016/29853
- Views 105
- Downloads 0
The Hypoglycemia Effect of Alkaloid Compounds from Oil Free Mahagony Seeds (Swietenia macrophylla, King)
Aim: To study the hypoglycemia effect of alkaloid compounds (Alkaloid crude extract) from oil free mahagony seeds (Swietenia macrophylla, King). Study Design: Experiments of alkaloid compounds isolation and in vivo test...
Phytochemical Screening, Antifungal and Antibacterial Effect of Zanthoxylum zanthoxyloides and Zanthoxylum macrophylum Used in Traditional Medicine in Yamboro (Central African Republic)
The knowledge of traditional medicine has always guided the search for new cures. Zanthoxylum zanthoxyloides and Zanthoxylum macrophylum, (Rutaceae) are used as medicinal plants in Central African Republic for bacteria a...
GC-MS Analyses of the Volatile Oil Constituents of the Leaf of Landolphia owariensis P. Beauv (Apocynaceae)
Aim: Evaluation of the volatile oil constituents of the leaves of Landolphia owariensis collected from Suleja, Niger State, North Central Nigeria in July 2015, where it is valued as an important medicinal plant used in f...
Cyathula prostrata: A Potential Herbal Hope for Hypertensives, an Animal Model Study and Its Secondary Metabolites Assessment via GC-MS
Aim: The use of folkloric therapy in the management of ailments such a hypertension is a global phenomena. Extracts of Cyathula prostrata are used as alternate antihypertensive in Nigeria. This paper evaluated the scient...
Evaluation of Antibacterial Activity of Five Selected Medicinal Plants in Tanzania against Gram Negative Bacteria
Aims: To evaluate antibacterial activity from five selected medicinal plants namely Embelia schimperi, Maerua decumbens, Ocimum gratissimum, Conyza floribunda and Plectranthus barbatus used for the management of bacteria...