Comparative assessment of microvascular decompression and gamma knife radiosurgery for trigeminal neuralgia: efficacy in pain alleviation and complication profiles
Journal Title: International Neuroscience Conference (NEURO-2023) - Year 2023, Vol 4, Issue 1
Abstract
Introduction: Trigeminal neuralgia (TN) represents an infrequent yet highly distressing condition characterized by unilateral, electric shock-like facial pain triggered even by the gentlest stimuli. In the therapeutic landscape, both Microvascular Decompression (MVD) and Gamma Knife Radiosurgery (GKRS) have emerged as notable interventions for addressing trigeminal neuralgia. This investigation endeavors to meticulously evaluate and juxtapose the efficacies and complication rates associated with these two treatments, specifically their role in alleviating pain for individuals afflicted by trigeminal neuralgia. Materials and Methods: A meticulously chosen cohort of 93 individuals diagnosed with trigeminal neuralgia was included in this study. Among them, 55 cases underwent MVD (Group A), while 38 cases underwent GKRS (Group B). Scrupulous recording of patient demographics transpired, accompanied by a comprehensive evaluation of pain relief outcomes, recurrence tendencies, and complications. Statistical methodologies congruent with the scope of the study were conscientiously employed. Results: Within Group A (mean age 56±8.2, 63% females), an impressive 80% of patients reported complete pain relief, whereas 15% experienced partial pain alleviation. Recurrence of pain manifested in a limited 5% of cases during the follow-up phase. Complications, encompassing cerebrospinal fluid leaks or wound infections, materialized in 7% of patients. In Group B (mean age 59.5±7.6, 68% females), a commendable 70% of patients achieved complete pain relief, with an additional 20% benefiting from partial relief. Recurrence of pain occurred in 10% of patients, while complications, primarily characterized by facial numbness or sensory disturbances, emerged in 5% of cases. Conclusion: Initial scrutiny of the gathered data unequivocally suggests that both MVD and GKRS manifest effectiveness in ameliorating pain experienced by patients grappling with trigeminal neuralgia. Remarkably, MVD exhibits an elevated prevalence of complete pain relief in comparison to GKRS. However, GKRS distinctly displays a lower incidence of complications. These findings offer valuable insights, accentuating the need for extended observations and comprehensive evaluations to ascertain the optimal therapeutic strategy for mitigating trigeminal neuralgia.
Authors and Affiliations
Otari Chankseliani, Tbilisi State Medical University, Tbilisi, Georgia.
Keywords
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