Comparative Clinical Study of 0.5% Hyperbaric Bupivacaine Alone and 0.5% Hyperbaric Bupivacaine with Midazolam Intrathecally for Lower Limb and Lower Abdominal Surgeries
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 4
Abstract
Aim: The present study was conducted to evaluate the efficacy and analgesic effect of mixture of midazolam-bupivacaine as compared to bupivacaine alone in patients undergoing lower limb and lower abdominal surgeries under subarachnoid block. Materials and Methods: The present study was conducted on 100 patients aged between 18 to 60 years belonging to ASA Grade I and II of both the sexes posted for lower limb and lower abdominal surgeries. Results: In 100 patients duration of sensory blockade in both group B and group M. the mean duration of sensory blockade in group B is 89.1±2.95 minutes were as in group M, it is 118.94±10.83 minutes, p<0.05, hence statistically significant. (t = 18.5918, p= 0.000, statistically significant). The mean duration of maximum motor blockade in B is 163.3±16.6 with a range being 135 to 210 minutes. In group M, the mean duration of maximum motor blockade is 180.24±27.40 minutes with a range being 152 to 245 minutes. As p value is 0.0004 it is statistically significant. (T=3.693, P value-0.0004, highly significant). In group B, the mean duration of analgesia is 125.46±7.18 minutes with a range of 110 to 142 minutes. In group M, the mean duration of analgesia is 243.26±24.41 minutes with a range of 173 to 273 minutes. In group B, the mean VAS score is 3.98±1 and in group M, it is 3.6±0.6. The t value is 2.869 and the p value is 0.005, hence there is statistical significance between them. Conclusion: It can be inferred that inj. midazolam 1 mg in combination with inj.bupivacaine 0.5% hyperbaric can be safely administered intrathecally for better postoperative analgesia.
Authors and Affiliations
Konkyana Suresh Kumar
Keywords
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- EP ID EP535336
- DOI 10.21088/ijaa.2349.8471.5418.1
- Views 118
- Downloads 0
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