COMPARATIVE EFFICACY OF 35% GLYCOLIC ACID PEEL VS. 20% SALICYLIC ACID PEEL IN THE TREATMENT OF POST ACNE SCARRING
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 19
Abstract
BACKGROUND Post acne scarring remains a common entity despite advances in the treatment of acne. A variety of modalities are available for post acne scarring, out of which chemical peels offer advantage of being non-invasive, painless, cheaper and easy to perform technique. Chemical peeling is the application of a chemical agent to the skin, causing controlled destruction of a part or whole of epidermis and/or a part of dermis. Aims and Objectives- To compare the efficacy of GA 35% vs. SA 20% in treatment of acne scars. MATERIALS AND METHODS This is a randomised comparative study of total 100 patients with post acne scarring. After taking the informed consent, they were randomised by computer generated random number table, which was allocated into 2 groups (50 each). One group received 35% glycolic acid (GA) peel and other 20% salicylic acid (SA) peel. A total of 3 sessions at an interval of 3 weeks. Response was graded on a five-point visual analogue scale. Since the calculated sample size was too high and thereby not feasible to include in this limited period of study, we had to limit the sample size for convenience. RESULTS Both SA and GA peels caused significant improvement in hyperpigmented scars. Although, SA peels had slightly better outcome when compared to GA peel, the difference was statistically not significant. The subjects found a greater final effect with SA, the mean score being 1.52 for GA peel and 1.92 for SA peel. Side effects were minimal and transient and there was no difference in the side effect profile between both the groups. CONCLUSION Both the agents (SA and GA) were equally effective and safe in Indian patients for post acne scarring and hyperpigmentation.
Authors and Affiliations
Asmita Jha, Karjigi Siddalingappa, Kallappa Herakal, Karan Malhotra, Harshavardhan Gowda
Keywords
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- EP ID EP418284
- DOI 10.14260/jemds/2018/545
- Views 99
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