Comparative Study between Efficacy of oral Misoprostol & Vaginal Misoprostol & Foley Bulb with oxytocin Induction in Prolonged Pregnancy and Study of Maternal & Fetal Outcome
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 1
Abstract
Background: The present study is undertaken to compare the safety and efficacy of 25ug oral Misoprostol with that of 25ug vaginal Misoprostol & foley bulb with oxytocin induction in prolonged pregnancy (>41 Weeks) & study of the maternal & fetal outcome. Methods: About 150 women are to be randomized to either oral Misoprostol or vaginal Misoprostol or foley bulb with oxytocin induction. The effect on labour induction and induction – delivery interval is studied. The mode of delivery, the maternal and fetal outcome between 3groups are compared. The cost effectiveness between 3 methods of induction is assessed. Results: Induction to delivery interval was shortest in oral Misoprostol group. Labour natural was maximum in oral Misoprostol group followed by vaginal Misoprostol. .The incidence of Meconium stained amniotic fluid was maximum in Oral Misoprostol. Tachysystole and Postpartum Haemorrhage, GIT effects was more in vaginal misoprostol. Conclusions: With this comparative study it is possible to reduce the perinatal mortality which is high in prolonged pregnancy and the rate of cesarean delivery due to failed induction in prolonged pregnancy. Hence would improve the maternal and fetal outcome.
Authors and Affiliations
Malini. S, L. Shanmuga vadivu
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