Comparative study between oral midazolam and oral ketamine as preanaesthetic medication in paediatric patients undergoing elective surgery: a randomized double blind study
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 2
Abstract
Introduction Prime objective of anaesthesiologist is to minimize adverse psychological and physiological effects of anaesthetic technique Premedication causes sedation and reduction of anxiety during separation from parents It also provides a calm and cooperative child for smooth induction of anesthesia We evaluated the differences in quality of premedication with orally administered midazolam and ketamine in the paediatric population undergoing elective surgical procedures and tried to ascertain the minimum interval required between premedication and parental separation Objective This study was undertaken to compare the efficacy and safety of oral midazolam and oral ketamine as a preanaesthetic medication for paediatric patients undergoing elective surgeryMaterials and Methods In this prospective randomized double blind study a total of 60 children aged 16 years belonging to ASA grade 1 and 2 scheduled for elective surgery were randomized into two groups of 30 each to receive either midazolam 05 mgkg Group A or ketamine 5 mgkg Group B orally Parameters to be assessed were quality of sedation and anxiolysis ease of parentchild separation and ease of venepunctureResults Overall success rate of midazolam for sedation and anxiolysis was higher than ketamine in all the time frames Successful separation from parents was easy in 25 patients 8333 in group A and 13 patients 4333 in group B Successful venepuncture was obtained in 9333 and 90 of patients in group A and group B respectively This higher rate of success during venepuncture was probably due to use of EMLA cream prior to venepunctureConclusion We concluded that premedication with oral midazolam 05mgkg provides better sedation and anxiolysis easy parent child separation than oral ketamine 5mgkgKeywordsMidazolam Ketamine Preanaesthetic Anxiolysis Venepuncture
Authors and Affiliations
Hachio William M. Yanthan, Tridip Jyoti Borah, Subrata Pahari, Tirtha Ratan Ghosh, Jaideep Sonowal
Keywords
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- EP ID EP476449
- DOI 10.18231/2394-4994.2018.0036
- Views 88
- Downloads 0
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