Comparative Study of Atorvastatin and Rosuvastatin on Serum Lipid Profile in Cardiac Patients with Diabetes
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 7
Abstract
Hyperlipidemia is a disorder of lipoprotein metabolism, which includes a number of abnormalities such as hypercholesterolemia and hypertriglyceridemia. Recently World Health Organization (WHO) has declared that by 2020, 60% of cardiovascular cases will be of Indian origin. Treatment of hyperlipidemia with statins has become an integral part of management of vascular diseases. Indications of statins have been greatly extended over the last 5 years subsequent to the publication of many multicenter prospective trials. There are multiple statins available in the Indian market like atorvastatin, simvastatin, pravastatin, pitavastatin, fluvastatin, cerivastatin and rosuvastatin. Hypolipidemic effect of statins is due to inhibition of hydroxymethylglutaryl-CoA reductase (HMG-CoA) and decrease in LDL-C is due to up regulation of LDL receptor activity The objective of this study is to evaluate and compare the efficacy and safety of Rosuvastatin 20 mg and Atorvastation 20 mg among cardiac patients with hyperlipidemia in diabetics and non diabetics.
Authors and Affiliations
Dr Ashish Sharma
Keywords
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