Comparative study of efficacy of intra nasal steroids in combination with antihistamines versus steroids alone as nasal spray in allergic rhinitis - Our experiences
Journal Title: Medpulse International Journal of ENT - Year 2018, Vol 6, Issue 2
Abstract
Background: To study and compare the efficacy of intranasal steroids in combination with antihistamines and steroids alone as nasal spray in allergic rhinitis Materials and Methods: It is a open design prospective study done between January 2017 to April 2018 on patients of allergic rhinitis data collected from multiple centre. A detailed history was taken and clinical examination of patient was carried out. 100 patients were taken up for study, following ARIA guidelines we classified allergic rhinitis patients and on the clinical severity NOSE Scores were done. Results: Pre and post treatment NOSE scores evaluated, statistical significance was evidenced in NOSE score (0.0007429), absolute eosinophil count (0.001612). Conclusion: Based on our study Azelastine and fluticasone combination was far superior as assessed by NOSE score. p value of combination group was 0.00074.there was more rapid decline in the AEC in group with azelastine and fluticasone combination and it was well tolerated in adults and adolescence.
Authors and Affiliations
Naveen Kumar Korivipati, P Ramakrishnaiah, Pavan Kumar, M Mallikarjun Rao, D Harshitha
Keywords
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