COMPARATIVE STUDY OF FENTANYL, BUTORPHANOL AND NALBUPHINE IN ATTENUATION OF HAEMODYNAMIC RESPONSES IN LAPAROSCOPIC CHOLECYSTECTOMY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 17
Abstract
BACKGROUND Numerous attempts have been made in the past to attenuate the haemodynamic responses occurring during laparoscopic cholecystectomy. The present study compared the effect of three opioids namely Butorphanol, Fentanyl and Nalbuphine in obtundation of haemodynamic responses in laparoscopic cholecystectomy in terms of Heart rate, BP (SBP, DBP and MAP) and secondary aim was to calculate duration of analgesia and sedation score. MATERIALS AND METHODS This was a randomised study comparing three opioid drugs- nalbuphine, fentanyl and butorphanol. It was carried out on 75 patients of either sex aged 18 - 60 years scheduled for elective laparoscopic cholecystectomy under GA. Subjects were enrolled into three groups- Group B (n= 25) patients received inj. Butorphanol 25 mcg/kg IV, Group F (n= 25) received inj. Fentanyl 2 mcg/kg IV and Group N (n= 25) patients received inj. Nalbuphine 0.2 mg/kg 5 minutes before the induction. RESULT At the time of extubation, mean MAP in Group B, F and N was 99.88, 95.32 and 97.24 respectively. This difference is highly significant when compared statistically (p value is 0.005). CONCLUSION With this study, we conclude that the administration of intravenous fentanyl and nalbuphine five minutes prior to induction of anaesthesia helps in better obtundation of haemodynamic responses to laparoscopic cholecystectomy than butorphanol.
Authors and Affiliations
Balwinder Kaur Rekhi, Tejinderpal Kaur Grewal, Parmod Kumar, Simrit Kaur, Priyanka Mehta
Keywords
Related Articles
- EP ID EP415176
- DOI 10.14260/jemds/2018/483
- Views 87
- Downloads 0
EVALUATION OF ROLE OF FAST VS CECT ABDOMEN IN DETECTING ORGAN INJURY IN BLUNT ABDOMEN TRAUMA PATIENTS
BACKGROUND There is rapid increase in the number of blunt abdomen injury patients, mainly due to road traffic accidents. The physical signs are often masked in these patients and usually there is delay in the diagnosis o...
FIXED DRUG ERUPTION- BANE OF A BOON
Medication forms one of the first basis of healing. But sometimes, like a double edged sword, it can do more harm than good. The pill that is used to cure an ailment may be the cause of misery itself. Drug reac...
EFFICACY OF WOUND INFILTRATION USING BUPIVACAINE VERSUS ROPIVACAINE ALONG WITH FENTANYL FOR POSTOPERATIVE ANALGESIA FOLLOWING ABDOMINAL HYSTERECTOMY UNDER SPINAL ANESTHESIA
[b]BACKGROUND[/b]: Wound infiltration with local anesthetics and opioids is increasingly being used as a part of multimodal postoperative analgesia. [b]OBJECTIVES[/b]: A prospective randomized double blind plac...
CUTANEOUS MANIFESTATIONS OF LUPUS ERYTHEMATOSUS FROM A TERTIARY CARE CENTRE IN COASTAL KERALA
BACKGROUND The aim of this study was to describe the Lupus Erythematosus (LE)-specific and LE-nonspecific cutaneous manifestations of lupus erythematosus. MATERIALS AND METHODS Cutaneous manifestations of lupus erythemat...
A COMPARATIVE STUDY OF AURAMINE STAINING USING LED FLUORESCENT MICROSCOPY WITH ZIEHL-NEELSEN STAINING IN THE DIAGNOSIS OF PULMONARY TUBERCULOSIS
[b]Background[/b]: Tuberculosis remains world’s leading cause of death from a single infectious agent. Pulmonary tuberculosis is the most common presentation of tuberculosis (TB). For developing countries with...