COMPARATIVE STUDY OF INTRA-ARTICULAR HYALURONIC ACID AND INTRA-ARTICULAR TRIAMCINOLONE HEXACETONIDE IN PRIMARY OSTEOARTHRITIS OF KNEE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 50
Abstract
BACKGROUND Intra-articular (IA) corticosteroid injection has an established therapeutic role, but the effect is short lasting. IA Hyaluronic acid (HA) is considered as a therapeutic alternative in patients who have failed non-pharmacologic and analgesic treatment. Aim of the study is to compare the efficacy and safety of IA HA with Triamcinolone hexacetonide (THA) in treatment of primary osteoarthritis (OA) knee. MATERIALS AND METHODS A descriptive cross-sectional study was done among 30 patients. One group (n=15) received IA THA 20 mg/2 mL on day 0 and other group (n=15) received IA HA 20 mg/2 mL on day 0, 7 &14 under aseptic precautions. The efficacy assessment using KGMC Score for pain, disability and functional impairment was done in 0-100 mm scale. Side effects if any were noted. RESULTS The present study revealed IA THA has superior short-term efficacy compared to IA HA. But HA has got long term superior efficacy. CONCLUSION OA being a chronic disease process, we need a drug which has a long lasting effect. Additive effect of HA & THA can be considered for better efficacy.
Authors and Affiliations
Sabeena Kizhedath, Haseena Kizhakkan Abboobacker, Gopesh Valoth, Bindhu Vasudevan
Keywords
Related Articles
- EP ID EP219653
- DOI 10.14260/Jemds/2017/830
- Views 77
- Downloads 0
ROLE OF OXIDATIVE STRESS IN TYPE 2 DIABETES MELLITUS
BACKGROUND Diabetes mellitus is a state of increased free radical activity and increased oxidative stress plays a major role in the development of diabetic complications. The present study was conducted to find the role...
MIDAZOLAM SYRUP AS A PREMEDICATION IN PAEDIATRIC PATIENTS- A RANDOMISED, DOUBLEBLIND, PARALLEL GROUP, PLACEBO-CONTROLLED STUDY
BACKGROUND Premedication is expedient in reducing the psychological trauma from recalling the unpleasant pre-anaesthetic phases; hence, inducing a trouble-free anaesthesia. Aim- This study was done to evaluate commercial...
THE CLINICAL STUDY OF GESTATIONAL DIABETES MELLITUS
[b] BACKGROUND[/b]: Gestational diabetes mellitus (GDM) is defined as glucose intolerance of variable degree with onset or first recognition during pregnancy. It accounts for 90% of the cases of diabetes mellitus i...
A STUDY ON PREVALENCE OF HYPERTENSION AND ITS RISK FACTORS AMONG URBAN ADULT POPULATION OF SHIMOGA.
[b]BACKGROUND:[/b] Hypertension is one of the very important public health problems our country is facing today, which is usually asymptomatic, readily detectable, having preventable risk factors and often leads to...
TO STUDY THE THYROID PROFILE IN POSTPARTUM PERIOD “A PROSPECTIVE STUDY”
BACKGROUND A healthy and well-functioning thyroid gland is important to everyone, but it is especially important to a woman in their child bearing age. Postpartum thyroiditis is a syndrome of transient or permane...