Comparative study of Labetalol v/s Methyl dopa in the Management of Gestational Hypertension
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 5
Abstract
Hypertensive disorders of pregnancy are one of the most common cause of maternal and perinatal mortality and morbidity affecting between 7-15 % of all pregnancies and are associated with as much as 22% of all perinatal deaths. They represent a group of conditions associated with high blood pressure, proteinuria and in some cases convulsions. The criteria for diagnosis & classification of the hypertensive disorders of pregnancy was according to the National High Blood Pressure Education Program Working Group (NHBPEP) and the American College of Obstetricians and Gynaecologists (ACOG). A total of 40 patients were included in this study, 20 of whom were given labetalol and 20 were given methyl dopa. During this period the maternal and foetal conditions were monitored along with control of hypertension. The outcome of therapy was based on the efficacy of the drugs in effective control of blood pressure, prolongation of pregnancy, mode of termination, requirement of additional drugs, side effects, and perinatal safety and outcome. Labetalol was found to be safer, quicker in achieving adequate control of blood pressure with considerable prolongation of the duration of pregnancy with fewer side effects on the mother as well as the neonate when used in the management hypertensive disorders of pregnancy.
Authors and Affiliations
Dr. Mahfrid. N. Dharwadkar
Keywords
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