COMPARATIVE STUDY OF LIVER FUNCTION TESTS IN DIABETES TYPE-2 PATIENTS AND NON-DIABETICS IN GUJARAT
Journal Title: International Journal of Basic and Applied Physiology - Year 2017, Vol 6, Issue 1
Abstract
Background: Diabetes mellitus is one of the major non-communicable diseases and the prevalence is rising globally. Abnormal liver function tests are not uncommon encounter in diabetes mellitus patients. Objective:-In this study aim was to find out the liver function test abnormalities in diabetic type-2 patients in Jamnagar, Gujarat. Material and Method: - this cross sectional study was conducted at the diabetic clinic in Guru Govind Singh General hospital, Jamnagar between May 2011 and May 2013, a total 200 patients were included. Parameters like serum Bilirubin (total & direct), total protein, serum albumin, alanine aminotransferase (ALT), alkaline phosphatase (ALP) used. Result:- 37% of diabetics type -2 patients had elevated total bilirubin value while in control group 6% had elevated value . Normal total protein, serum albumin level in both groups. Raised ALT were noted in 39 % of diabetes type -2 patients while in control group 6% had elevated value. Elevations in serum alkaline phosphatase (ALP) were found in 38 % of diabetic type – 2 patients while in control group had not much elevated value. Mean value of ALT & ALP had no correlation with gender of the diabetes patients. Conclusion: - abnormal liver function results are more common among diabetes patients. There were not significant changes in parameters like serum Bilirubin (total & direct), total protein, serum albumin. But elevated ALT and ALP are the markers for associated non-alcoholic fatty liver disease in diabetes patients.
Authors and Affiliations
Vishaldeep Gohel, Betsy Johnson, Varsha S Joshi
Keywords
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