COMPARATIVE STUDY OF PLACENTAL CHANGES IN MILD AND SEVERE HYPERTENSIVE DISORDERS OF PREGNANCY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 90
Abstract
BACKGROUND The present study is undertaken to analyse placental changes in the mild and severe hypertensive disorders of pregnancy with a view to assess the significance of placental changes, which may serve as a guide to the severity of disease and complications. The aims of this study are: 1. To study histopathology of the placenta in cases of mild and severe hypertensive diseases of pregnancy. 2. To correlate the pathological changes in the placenta with severity of hypertension. 3. To study spectrum of features in placenta that could be responsible for the manifestation of complications of pregnancy. MATERIALS AND METHODS 100 cases of women with hypertensive disorders complicating pregnancy including gestational hypertension, preeclampsia, eclampsia, preeclampsia superimposed on chronic hypertension and chronic hypertension are taken. Retrospective hospital based study of 100 cases over a period of one year from January 2015 to 2016 in RIMS, Srikakulam (AP). RESULTS In the present study, the mean placental diameter was found to be decreased in severe hypertensive group than the mild group. In the present study, calcification were associated with severity of hypertension and retroplacental haematomas were more with severity of hypertension in pregnancy. The mean placental diameter was found to be decreased in severe hypertensive group than the mild group. Calcification were associated with severity of hypertension and retroplacental haematomas or more with severity of hypertension in pregnancy. The infarctions were more with severe group of hypertension. CONCLUSION From the present study, it can be concluded that hypertensive disorders complicating pregnancy adversely influence the morphology of placenta, more so in severe hypertensive cases than in mild hypertensive cases.
Authors and Affiliations
Tulugu Sasikala, Parvathi D, Indira K
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