Comparative Study of Ropivacaine with Dexmedetomidine versus Ropivacaine Alone in Supraclavicular Brachial Plexus Block for Upper Limb Surgery
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 6
Abstract
Background and Aims: Supraclavicular plexus block, as a regional anesthesia has taken over as principal technique for upper limb surgeries. Ropivacaine is long acting local anesthetic drug considered to produce less neurotoxicity and cardiotoxicity. Dexmedetomidine has been reported as an effective adjuvant for regional anesthetic agents. The present study was conducted to compare and evaluate the effectiveness of ropivacaine with dexmedetomidine versus ropivacaine alone in supraclavicular brachial plexus block for upper limb surgeries. Materials and Methods: Sixty patients aged between 19 and 50 years with ASA grade 1 or 2 posted for elective upper limb orthopedic surgeries were included in the study and were randomly divided into 2 groups with 30 patients in each group. Group R: 0.75% ropivacaine (30 cc) and Group RD: 0.75% ropivacaine (30 cc) + dexmedetomidine 1 μg/kg. Both groups were compared for complete onset time and total duration of sensory blockade, complete onset time and total duration of motor blockade and total duration of analgesia. Result: The mean onset time for a complete sensory block in Group R was 20.1 ± 1.62 min, in Group R + D was 17.6 ± 1.25 min (P = 0.001) and the mean onset time for complete motor block in Group R was 24.5 ± 1.48 min, and in Group R + D was 22.5 ± 1.50 min (P = 0.00001) which was statistically significant. The mean duration of sensory block in Group R was 561.0 ± 33.87 min and in Group R + D was 790.3 ± 41.23 min and the mean duration of motor block in Group R was 508.0 ± 17.89 min, and in Group R + D was 680.7 ± 69.38 min which was statistically significant (P = 0.00001). The mean duration of analgesia in Group R was 298.33 ± 70.36 min and in Group R + D was 406.17 ± 73.15 min which was statistically significant (P = 0.00001). Conclusion: Dexmedetomidine as an adjuvant to ropivacaine in the supraclavicular brachial block for upper limb surgery significantly shortens the onset time for sensory and motor block and prolongs the duration of sensory and motor blocks with longer duration of post-operative analgesia.
Authors and Affiliations
Vinit Khemka, Priti D Jadeja
Keywords
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