Comparative Study of Varying Doses of Dexmedetomidine Combined with Levobupivacaine in Supraclavicular Brachial Plexus Block: A Randomized Double-Blind Prospective Study
Journal Title: International Journal of Research and Review - Year 2018, Vol 5, Issue 11
Abstract
Background: Regional anesthesia is a recommended technique for upper and lower limb surgeries with better postoperative profile. The ideal dose of dexmedetomidine for brachial plexus block is a matter of debate. Few studies compared the effect of different doses of dexmedetomidine. Aims and Objectives: This study was carried out to evaluate 50 μg or 100 μg of dexmedetomidine added to 0.5% levobupivacaine, with regard to the duration of analgesia. Materials and Methods: 120 patients undergoing upper limb surgeries under supraclavicular brachial plexus block were randomly allocated into two groups. Group LD50 (n=60) received 29 ml of 0.5% levobupivacaine plus 50 μg of dexmedetomidine diluted in 1 ml of normal saline. Group LD100 (n=60) received 29 ml of 0.5% levobupivacaine plus 100 μg of dexmedetomidine diluted in 1 ml of normal saline. Duration of analgesia was the primary outcome observed. Results: The duration of analgesia was significantly prolonged in group LD100 when compared to LD50 group (P = 0.001). Significantly fewer patients in group LD100 required rescue analgesia. Conclusion: Dexmedetomidine 100 μg used for brachial plexus block showed quicker onset and prolonged duration of sensorimotor blockade and analgesia, but had higher incidence of bradycardia and sedation.
Authors and Affiliations
Dr. Inugala Rajkumar Reddy
Keywords
Related Articles
- EP ID EP482646
- DOI -
- Views 79
- Downloads 0
Lycopene and Cardiovascular Diseases: A Review of the Literature
Cardiovascular diseases (CVD) are the leading causes of human disability and premature death throughout the world. Diet has a direct link with the development of CVD and so dietary change is the current approach for the...
Clinico-Etiological and Socio-Economic Profile of Children (1-12 Years of Age) With Epilepsy
Epilepsy is a significant cause of morbidity and mortality in children. A comprehensive clinico-etiological and socio-economic data on epilepsy is crucial in implementing an effective management strategy. Therefore, this...
Learning Motivation of Students During the Implementation of Lecturing Based in Silico Approach
The silico-based learning is one of the new curriculum programs for prospective teachers at UN PGRI Kediri. Because of motivation plays an important role, this study aims to reveal the dimension of students' learning mot...
Working Conditions of Female-Headed Households in Jammu and Kashmir, with Special Reference to District Budgam
Women in the workforce earning wages or a salary are part of a modern phenomenon, one that developed at the same time as the growth of paid employment for men, but women have been challenged by inequality in the workforc...
Pretreatment of Water before Application of Membrane Separation: Focus on NOM Removal
Water reuse and recycle is becoming important for conservation of water resources. Primary, secondary and tertiary treatments with physical, biological and chemical techniques are conventionally used for treatment. The p...