COMPARATIVE STUDY ON LIPID PEROXIDATION AND ANTIOXIDANT VITAMINS E AND C IN FALCIPARUM AND VIVAX MALARIA
Journal Title: Indian Journal of Clinical Biochemistry - Year 2006, Vol 21, Issue 2
Abstract
Reactive oxygen species are thought to be involved in the pathogenesis of Malaria. To assess the extent of oxidative stress, a study was conducted in patients with Plasmodium falciparum malaria and Plasmodium Vivax malaria. Plasma Thiobarbituric acid reactive substances(TBARS) were measured to assess the degree of lipid peroxidation. Antioxidant status was measured by estimating the levels of Vitamins E and C. Results were compared with age and sex matched control subjects. This study suggests that plasma TBARS levels were significantly increased in malaria patients. The patients with P. falciparum infection showed significantly increased levels of lipid peroxides when compared to P. vivax malaria. The antioxidant Vitamins E and C were decreased significantly in malaria patients in both the groups. Maximum decline in Vitamin C was observed in P. vivax malaria. Therefore it is been hypothesized that antioxidant Vitamins E and C could provide protection against the oxidative stress induced by malaria.
Authors and Affiliations
Prasannachandra , Vivian D’Souza , Benedicta D’Souza
Keywords
Related Articles
- EP ID EP102014
- DOI -
- Views 129
- Downloads 0
PARAOXONASE ACTIVITY AND ANTIBODIES TO OXIDIZED-LDL IN CHRONIC RENAL FAILURE PATIENTS ON RENAL REPLACEMENT THERAPY
Serum paraoxonase (PON1) and antibodies to oxidized-LDL (anti ox-LDL) were measured in chronic renal failure subjects on renal replacement therapy such as hemodialysis (HD) peritoneal dialysis (PD) and transplantation...
EVALUATION OF URINARY ABNORMALITIES IN NEPHROLITHIASIS PATIENTS FROM MARATHWADA REGION”
Urinary abnormalities were evaluated in 100 renal stone patients with first episode of renal stone having age 22 to 45 years from both sex and compared to 100 normal healthy control group having same age group from bot...
POST PRANDIAL PLASMA GLUCOSE LEVEL LESS THAN THE FASTING LEVEL IN OTHERWISE HEALTHY INDIVIDUALS DURING ROUTINE SCREENING
ABSTRACT During routine screening, some otherwise healthy individuals who showed remarkably lower post prandial (at 2 hour) plasma glucose without any symptom were subjected to extended glucose tolerance test and a fe...
ANTIDIABETIC EFFECT OF T. ARJUNA BARK EXTRACT IN ALLOXAN INDUCED DIABETIC RATS
The present study was carried out to evaluate the antidiabetic effect of T.arjuna stembark extract and to study the activities of hexokinase, aldolase and phosphoglucoisomerase, and gluconeogenic enzymes such as glucos...
EFFECTS OF SHORT-TERM HORMONE REPLACEMENT ON ATHEROGENIC INDICES IN INDIAN POSTMENOPAUSAL WOMEN
Indian ethnicity by itself is a strong risk factor for development of CAD in Indian postmenopausal women due to lower HDL levels as compared to Whites and women of oriental origin. We evaluated and compared the short-...