Comparing the effects of Bupivacaine and Ropivacaine Instillation for Postoperative Analgesia in Patients Undergoing Lumbar Spine Surgery: A Prospective Randomised Double Blind Study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 5
Abstract
Introduction: Laminectomy is associated with considerable postoperative pain. Providing analgesia locally in the area of surgical trauma, with minimal systemic side effects has become an integral part of multimodal analgesia. The objective of this study is to compare the effects of bupivacaine and ropivacaine instillation for postoperative analgesia in patients undergoing lumbar spine surgery. Methods: The study was conducted in a double blind manner. 40 ASA I & II patients scheduled for lumbar laminectomy were randomly divided into two groups to receive either 20 ml (0.25%) of bupivacaine (group B) or ropivacaine (0.25%) instillation into the wound after securing hemostasis. After a dwell time of 60 sec the wound was closed in layers without mopping or suctioning. After extubation, the pain scores were evaluated by Numerical rating scale at 0 hours i.e., immediately after extubation and then at every 1 hour up to first 8 hours and then at every 6 hours till 24 hours and also the time for first demand of analgesia, number of analgesic demands and the total amount of analgesia consumed were noted by an independent observer. Results: The area under curve for mean pain score over 24 hrs time period on the basis of NRS scale was 46.8±5.84 in ropivacaine group (R) and 44.78±5.36 in bupivacaine group (B) with p= 0.26. The duration of analgesia and number of demands and the amount of analgesia consumed was also found statistically not significant. Conclusion: Surgical wound instillation with bupivacaine and ropivacaine provided better analgesic effect and safe postoperative analgesia in patients undergoing laminectomy surgeries
Authors and Affiliations
Jay Brijesh Singh Yadav
Keywords
Related Articles
- EP ID EP515777
- DOI -
- Views 58
- Downloads 0
Role of Diagnostic Laparoscopy in Evaluation of Infertile Women -A Retrospective Study
Background: The aim of the study is to detect the role of diagnostic laparoscopy in detecting uterine, ovarian and pelvic pathologies in infertile women. It should be offered to all infertility cases who have completed a...
Reward Pathway in Brain and Alcohol Dependence: A Co-Relation Study in Wistar Rats to Show the Effect on Brain Dopamine, Dihydrophenylacetic Acid (DOPAC) and Homovanilic Acid (HVA)
Humans, as well as other organisms engage in behaviors that are rewarding. The pleasurable feelings provide positive reinforcement so that the behavior is repeated. Each of the naturally rewarded behaviors is required fo...
Effects of Anti Inflammatory Agents Following Cataract Surgery
Objectives: To assess and compare the analgesic and anti inflammatory efficacy of nepafenac and prednisolone eye drops used individually and in combination in post-operative period of cataract surgery by estimating anter...
A Clinical Study on Pre-Eclampsia and Thyroid Hormone Alteration in Women Presenting to Tertiary Care Institute of North India
Background: The obstetricians are increasingly becoming aware of the potential or adverse effects of hypothyroidism on the outcome of pregnancy. Preeclampsia and eclampsia are major causes of maternal and perinatal morbi...
Treatment Outcome of Triple Negative Breast Cancer- A Retrospective Study from Regional Cancer Centre Kashmir
Abstract