Comparison between Clonidine and Nitroglycerine in Maintaining Stable Cardiovascular Status in Laparoscopic Cholecystectomy Surgery
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6
Abstract
laparoscopic cholecystectomy has revolutionized gall bladder surgeries and it has now become the “gold standard” of symptomatic cholelithiasis. It offers many benefits than conventional cholecystectomy, and has been promoted, as a “gentle surgery”. Laparoscopic cholecystectomy combines the benefits of completely removing the gall bladder with the advantages of shorter hospital stays, more rapid return of normal activities, less pain associated with small limited incision and less postoperative ileus compared with the open laparotomy technique. However, this procedure is not risk free. In fact it produces significant hemodynamic changes. Clonidine, an imidazoline derivative is selective α2 adrenergic agonist. It produces a fall in heart rate and blood pressure associated with decrease in systemic vascular resistance and cardiac output. Nitroglycerine, 1,2,3 propanetrioltrintirate a vasodilator, is active on both arteries and veins.
Authors and Affiliations
Dr Arata Kumar Swain
Keywords
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