Comparison Between Intravaginal Misoprostol (PGE1) and Dinoprostone (PGE2) in Induction of Labour
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 5
Abstract
Introduction: Induction of labour is needed in many patients to improve outcomes of pregnancy. It is important to identify the most suitable agent to assist the progression of natural labour. Aims & Objectives: To conduct a comparative study on the efficacy and safety of two prostaglandin analogues misoprostol (PGE1) and dinoprostone (PGE2) in inducing a normal vaginal delivery. Material & Methods: One hundred patients were randomly divided into misoprostol (n=50) and dinoprostone (n=50) groups. These groups were comparable in terms of period of gestation, gravidity and indication for induction of labour. Results: We found that misoprostol was able to significantly (p-0.009) lower the mean duration of induction (320.6min) when compared to dinoprostone (417.2 min). In our study, misoprostol induction was successful in 90% of all cases, whereas dinoprostone induction was successful in 82%. The side effects profiles of both groups were similar and only minor side effects were noted with both misoprostol (n-12) and dinoprostone (n-6). Conclusion: Misoprostol lowers the mean duration of labour and has a slightly higher success rate than dinoprostone in inducing labour. Hence it may be used an alternative to dinoprostone successfully & safely.
Authors and Affiliations
Sadhana Singh, Nutan Narayan, Meena Sinha, Rajul Rastogi, Pragya Sinha
Keywords
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- EP ID EP547543
- DOI 10.21276/ijmrp.2017.3.5.026
- Views 79
- Downloads 0
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