Comparison of Antibacterial Effect of Fluoride and Chlorhexidine on Two Cariogenic Bacteria: An in Vitro Study
Journal Title: Journal of Dental Biomaterials - Year 2014, Vol 1, Issue 1
Abstract
Statement of problem: Dental plaque is the main source for dental caries and there is no proper vaccine that can affect dental plaques. Objectives: Daily use of an efficient anti-plaque product can be very beneficial in plaque control and, thus, prevention of caries. This study aims to evaluate the antibacterial effects of four products of Chlorhexidine and Fluoride on two types of cariogenic bacteria. Materials and Methods: In this in vitro study, the antibacterial effect of Chlorhexidine and Fluoride (gel and solution) against Streptococci Sanguis and Sobrinus was evaluated. Chlorhexidine gluconate 1% gel (Corosodyl, France), Chlorhexidine gluconate 2% solution (Consepsis, Ultradent, US), Sodium fluoride 0.2% solution (Oral-B, US) and Acidulated Phosphate Fluoride 1.23% gel ( Denti-Care, Canada) were used. The disc diffusion method was used for testing bacterial sensitivity. The data were analyzed using paired t-test and Chi-square test. Results: In comparison with the negative control, each of the four gels and solutions showed antibacterial effects but the effects were not statistically significant for fluoride solution (P=0.217). For S. Sobrinus, the mean diameter of inhibition zone around the discs coated with fluoride gel (F g), fluoride solution (F s), Chlorhexidine gel (CHX g) and Chlorhexidine solution (CHX s) were 19, 9, 21.5 and 27.5mm, respectively. For S. Sanguis, the mean diameter of inhibition zone around the discs coated with F g, F s, CHX g and CHX s were 17, 11, 17 and 25mm, respectively. CHX s had the most effect on both bacteria and F s had the least. CHX g and F g were less effective than CHX s, respectively. Conclusion: The results demonstrated that 2% CHX s and 1.23% F g can be effective on inhibition of the growth of some of cariogenic bacteria. Therefore, these agents can be used in the prevention of Early Childhood Caries.
Authors and Affiliations
HR Poureslami, F Barkam, P Poureslami, Z Salari, S Salari
Keywords
Related Articles
- EP ID EP248961
- DOI -
- Views 71
- Downloads 0
Chemical Stability of Bioglass in Simulated Oral Environment
Statement of Problem: Bioglasses are a series of biocompatible dental materials, which are considered as light conducting inserts in resin composite restorations. Consequently, their chemical stability is more essential...
Concentration of Calcium, Phosphate and Fluoride Ions in Microbial Plaque and Saliva after Using CPP-ACP Paste in 6-9 year-old Children
Statement of Problem: Dental caries is one of the most common chronic diseases in children. The balance between demineralization and remineralization of the decayed teeth depends on the calcium and phosphate content of t...
The Effect of Two Types of Denture Adhesive on the Satisfaction Parameters of Complete Denture Wearers
Statement of Problem: Patient satisfaction is highly influenced by the retention of the denture. In some instances using denture adhesives may help the patient to achieve this goal. Objectives: The purpose of this study...
Comparing the Accuracy of Silicone and Polyether in Reproducing Gingival Height for Implant Supported Crown: an in vitro study
Statement of Problem: Accurate impressions are one of the most critical factors in achieving acceptable restorations. When pouring the impressions of implant supported restorations, soft materials like silicone and polye...
A One-Year Evaluation of a Free Fissure Sealant Program
Statement of Problem: Pit and fissure sealant therapy has been approved as an effective measure in the prevention of occlusal dental caries. Resin based ma- terials are the most common materials used worldwide. A variety...