“Comparison of C-Reactive Protein in Chronic Obstructive Pulmonary Disease and During Acute Exacerbation”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Introduction:- Persistent reduction in FEV1 (Forced Expiratory Volume in first second) is one of the most typical finding in COPD along with airflow limitation . Patients with airflow obstruction due to COPD have reduced ratio of FEV1/FVC. Chronic inflammation in pulmonary tissues is also associated with systemic effect which is evident from the association between pulmonary compartment and peripheral tissues leading to the concept of COPD as a systemic inflammatory disease. Components of the systemic inflammation such as cytokines, inflammatory markers like C- reactive protein (CRP) are potential markers that can be used in the diagnosis and prognosis of chronic obstructive pulmonary disease Aim:- To Compare the CRP levels in stable COPD patients and in patients with acute exacerbation of COPD(AECOPD). Materials And Methods:-Study design-cross sectional study Source of data: 100 outpatients& inpatients diagnosed as COPD in pulmonology and medicine departments at Tertiary Care Hospital, were enrolled in the study Results:- The mean CRP in AECOPD is 5.486 and in stable COPD is 2.182 which is statistically significant there by suggesting that CRP can be used as a marker of severity
Authors and Affiliations
Dr. K. Swaminathan, Dr. M. Rajesh Kumar
Keywords
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- EP ID EP244777
- DOI 10.9790/0853-1610131315
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