Comparison of Predebridement and Debridement Cultures in Predicting Postoperative Infections in Compound Fractures
Journal Title: Journal of Clinical and Diagnostic Research - Year 2018, Vol 12, Issue 7
Abstract
Introduction: Compound fractures are fractures which communicate to the external environment through a wound, exposing the bone. Bacterial contamination is reported to occur in 60-70% of the cases which may be responsible for the infectious complications in these patients. This study has aimed to predict the appropriate time of culture, its frequency and the type of specimen to be processed for determining the microbial flora of the fracture wound which will help in instituting rational antibiotic treatment for the patient. Aim: To compare predebridement and debridement cultures in causing postoperative infections in patients with compound fractures of long bones. Materials and Methods: This was a prospective study conducted at Madras Medical College for a period of six months involving 100 samples consisting of sequential swabs and tissue specimens sent to the Microbiology laboratory for investigation. Results: In the predebridement period, within six hours of injury, 15% of the cultures showed significant growth out of which Staphylococcus aureus was isolated in 53%. Among the debridement cultures 41% showed significant growth. Postoperative follow up was done for six weeks. Forty six percent of patients showed clinical signs of infection. Thirty nine percent of patients turned out to be culture positive confirming the presence of postoperative infection. It was noted that 53 percent of predebridement culture positive patients continued to have persistent infection in the postoperative period and 66% of the debridement culture positive patients developed postoperative infection. It was concluded that the sensitivity of predebridement cultures and debridement cultures were 21% and 69% respectively. Conclusion: It is therefore recommended that debridement culture with a higher sensitivity will provide guidance regarding the choice of antimicrobial therapy.
Authors and Affiliations
Adisesh Mangala, Krishnarao Arthi, R Deepa
Keywords
Related Articles
- EP ID EP522763
- DOI 10.7860/JCDR/2018/36011.11735
- Views 64
- Downloads 0
Healthcare Associated Infections in a Resource Limited Setting
Introduction: Health Care associated Infections (HAI) are the most common complications affecting the hospitalized patients. HAI are more common in developing and under developed countries. However, there are no systemat...
Evaluation of the Role of HBA1c in Chronic Kidney Disease
Introduction: Chronic Kidney Disease (CKD) refers to a group of heterogeneous disorders that results in gradual loss of structure and function of the kidneys. Aim: To evaluate the role of glycated haemoglobin (HBA1c) due...
Quality of Life and Nutritional Status of People Living with HIV/AIDS (PLHA’s) in Western Maharashtra-A Prospective Cohort Study
ABSTRACT Introduction: Decades ago HIV/AIDS epidemic was considered as unprecedented human catastrophe. With Anti-Retroviral Therapy (ART) services easily available and accessible to everyone, HIV/AIDS has become a chron...
Clinicopathological Profile of Cutaneous Metastasis from Internal Malignancies: A Five Year Retrospective Study
ABSTRACT Introduction: Cutaneous metastasis is the infiltration of skin by malignant cells from an underlying internal malignancy. Aim: To analyse clinicopathological profile of patients with cutaneous metastasis from in...
Olmesartan in Management of Proteinuria
ABSTRACT Proteinuria is a marker and predictor of cardiovascular morbidity and mortality. Blockade of angiotensin receptor might result in reduction in proteinuria. Olmesartan, an Angiotensin Receptor Blocker (ARB) whic...