Comparison of Serum Follicle-Stimulating Hormone and Bone Mineral Density Levels in Natural Menopause and Surgical Menopause Women
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 8
Abstract
Introduction: Menopause is characterized by reduced levels of ovarian hormones, especially estradiol by 66%, and increased in follicle-stimulating hormone (FSH) due to negative feedback mechanism. While this reduction occurs gradually in women with natural menopause, it occurs suddenly in surgical menopause. Our study is aimed at comparing serum FSH levels and bone and mineral density (BMD) levels in women with surgical and natural menopause. Materials and Methods: The study was conducted on 90 women, of whom 30 were healthy menstruating women in the age group of 20–30 years, who are taken as control group. Of 60 remaining, 30 women were taken who have attained their menopause naturally within the age of 42–58 years. The remaining are women who have attained their menopause surgically in the age group of 35–50 years. These study groups were selected randomly and their FSH levels and bone mineral density were measured and compared between these groups. Results: The FSH levels were statistically significantly higher in natural menopause and surgical menopause groups when compared with control group. Significant difference was observed in the FSH levels of the natural and surgical menopause groups also. The bone mineral density was higher in control groups than the natural and surgical menopause groups and no significant difference between the natural and surgical menopause groups. Conclusion: The raised levels of FSH and decreased levels of BMD suggest increased risk of osteoporotic changes in the persons who have been hysterectomized.
Authors and Affiliations
Dodda Surekha, P Hannah Himabindu
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