Comparison of Specific Bone Biomarkers in Cronic Kidney Disease Bulgarian Patients with secondary hyperparathyroidsm

Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2

Abstract

Secondary hyperparathyroidism (sHPTH) is one of the most common complications of CKD (chronic kidney disease), which alters the mineral balance with the development of bone mineral disorders and soft tissue calcifications. The treatment of bone-mineral disorders requires continuous monitoring of Ca-P exchange, PTH (parathyroid hormone), serum Vitamin D levels and the protein bone markers - osteocalcin, bone alkaline phosphatase - BAP. In the Clinic of Dialysis at University Hospital "St. Marina " are followed and compared serum biomarker levels - BAP, Osteocalcin, Vit D in two groups of patients-dialysis and CKD patients in 2 and 3 stage with sHPTH. The results show statistically significant differences between the mean values of the two groups and between female and male in the tested serum levels of the indicators.

Authors and Affiliations

Sv. Staykova 1, Y. Bocheva, K. Prodanova

Keywords

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  • EP ID EP361588
  • DOI 10.9790/0853-1702048590
  • Views 50
  • Downloads 0

How To Cite

Sv. Staykova 1, Y. Bocheva, K. Prodanova (2017). Comparison of Specific Bone Biomarkers in Cronic Kidney Disease Bulgarian Patients with secondary hyperparathyroidsm. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 17(2), 85-90. https://europub.co.uk./articles/-A-361588