COMPARISON OF VOLATILE COMPOSITION OF SUPERCRITICAL CARBON DIOXIDE EXTRACT FROM RHIZOMES OF KOREAN MEDICINAL PLANT ‘CHUN-KUNG’ (CNIDIUM OFFICINALE MAKINO) BY DIRECT-AND SPME-GC/MS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 9
Abstract
Objective: The main purpose of this study was to evaluate the volatile composition of supercritical fluid extract (SFE) obtained from Cnidium officinale Makino rhizomes.Methods: GC/MS analyses were carried out with the direct- and solid phase microextraction (SPME) of SFE obtained from rhizomes. In addition, GC/MS analysis was performed for the rhizomes of C. officinale using SPME.Results: SPME-GC/MS analysis of the rhizomes revealed the separation of 23 components. Among these, β-phellandrene (20.38%), dictyotene (12.98%), β-pinene (10.59%), β-selinene (9.45%), eugenol (7.71%) and β-farnesene (7.09%) were found to be major components. In the SFE analyzed by direct-GC/MS, linoleic acid (19.26%), 2-methoxy-4-vinylphenol (18.98%), hexadecanoic acid (12.15%), and β-selinene (9.44%) were identified as major components. Whereas, 3,4-dihydrocoumarin (16.94%), shyobunone (14.07%), dictyotene (10.65%), p-cresol (10.17%), zierone (6.36%) and umbellulone (5.71%) were major components in the SFE analyzed by SPME-GC/MS.Conclusion: The present study clearly suggested that the SPME-GC/MS analysis of SFE provided the separation of more number with diverse groups of compounds than the direct-GC/MS.Â
Authors and Affiliations
Bo-ram Yeon, Songmun Kim, Kandhasamy Sowndhararajan, Ji-wook Jung, Jin-woo Jhoo
Keywords
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