COMPARISON STUDY BETWEEN THREE NON INVASIVE METHODS USED FOR DIAGNOSING HELICOBACTER PYLORI INFECTION
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 10
Abstract
Background: Helicobacter pylori (H. pylori) is a Gram-negative, microaerophilic bacterium it is one of the most common human-specific pathogens which exclusively inhabits the gastric mucosa. Infection with H. pylori is always associated with chronic gastric inflammation, gastritis and peptic ulceration which can lead to gastric cancers such as adenocarcinoma. The aim of this study was to compare between three non invasive methods used for diagnosing Helicobacter pylori infection. Methodology: this study was conducted in Khartoum state from February to May 2017. Stool and serum samples were collected from 105 patients with gastric disorders. The presence of H.pylori infection was evaluated by urea breath test, stool antigen detection test and antibody detection test. Results: A total number of 45 patients gave positive result in urea breath test while 60 patients' showed negative result.44 patients gave positive result in stool antigen test while 61 patients showed negative result. A total number of 40 patients gave positive result in antibody detection test while 65 patients' showed negative result. The result showed that the similarity between urea breath test, stool antigen test, urea breath test, antibody detection test and stool antigen test, antibody detection test was 99%, 72,4% and 71,4 % respectively. While the similarity between these three method was 69.5%. Conclusion: In this study there was no significant differences between these three non invasive methods. The combination of antibody detection and stool antigen test or using urea breath test only can significantly improve the detection of H. pylori infection.
Authors and Affiliations
Mohamed Assadig Ahmed Hussein
Keywords
Related Articles
- EP ID EP629153
- DOI -
- Views 152
- Downloads 0
EFFECT OF ORAL ADMINISTRATION OF FORSKOLIN, HOMOTAURINE, RUTIN, L-CARNOSINE, MAGNESIUM, VITAMINS B1, B2, B6 AND FOLIC ACID ON PATTERN-ELECTRORETINOGRAM AND VISUAL FIELD PARAMETERS IN GLAUCOMATOUS PATIENTS
This is a review article about the potential neuroprotective activity of forskolin, a receptor-independent activator of adenylate-cyclase, associated to homotaurine, rutin, L-carnosine, vitamins B1, B2, B6, magnesium and...
REVIEW ARTICLE - COSMECEUTICALS: HERBS USED AS COSMETICS
Herbal medicine is now used by over half of the population of the world for healthy living. Modern medicine is rooted in ethnobotanical traditions using indigenous flora to treat symptoms of human diseases or to improve...
ASSOCIATION BETWEEN IRON DEFICIENCY AND HELICOBACTER PYLORI INFECTION AMONG SUDANESE PATIENTS IN KHARTOUM STATE – 2018
Helicobacter pylori (H. Pylori) are a Gram-negative spirally shaped bacterium. Infection rates are strongly related to poor living conditions; also iron deficiency (ID) is most common nutritional deficiency that associat...
PHYTOCHEMICAL INVESTIGATION, CYTOTOXICITY, ANTIBACTERIAL AND ANTI-OXIDANT ACTIVITY OF OLEA EUROPEA FRUITS GROWN IN OMAN
Olea europaea (syn. Zaytoun) belonging to the family Oleaceae is a small evergreen tree, from 12 to 20 feet high. It is reported to contain various flavonoids, steroids, phenolic compounds proteins and lipids. Biological...
REVISITED DENTAL WEAR- A REVIEW ARTICLE
Tooth wear is an ever – increasing problem, and younger patients are particularly at risk. The problem is likely to continue as patients demand and expectations rise and as more natural teeth are retained into old age. I...