ComparisonofTwoDosesofCisatracurium(0.15mg/Kgand0.2mg/Kg)inaSingleCentre,Prospective,Comparative,ParallelGroupofPatientsUndergoingGeneralAnesthesiawithEndotrachealIntubationbyStudyingEaseofIntubation
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2023, Vol 3, Issue 1
Abstract
Objective:Studytheadvantagesandpitfallsofboth0.15mg/kgand0.2mg/kgofCisatracuriumforIntubation.Background:ThepatientscomingtoaTertiaryCareHospitalduringperiod2018-2019forsurgeryunderGeneralAnaesthesia,whomettheInclusionCriteriawerestudiedinahundredpatients.Aftergivingallcomponentsofbalancedgeneralanaesthesia,patientsrandomisedinto2groupseither0.15mg/kgor0.2mg/kgofCisatracuriumasamusclerelaxantandIntubationwasdoneat3minutes.MeasurementsandResults:Heartrate,Bloodpressure,Systolic,Diastolic,Mean,SpO2,ETCO2,TOFmonitoringattheadductorpollicis,andBISweremonitoredfor7minutesandIntubatingconditionsinboththegroupswereevaluated,andscoredaccordingtotheSteyn’sModificationofHelbo-HansenScoringsystem.InhaemodynamicchangesinGroupA[0.15mg/kg]HeartrateandBloodpressureshowedanincreasingtrendbeforecomingdowntobaselineby7minutes.InGroupB[0.2mg/kg]thetrendwasdecreasingfrombaselineafteraminorincreaseinheartrateat2minutesandMeanBloodpressurewasloweratallintervalswhencomparedtobaseline.RegardingIntubationInGroupAmaximumnumberofparticipantswerehavinggoodscore(56%)followedbypoor(30%)andexcellent(14%)whereasinGroupBexcellentscorewasmaximum(62%)followedbygood(32%)andpoor(6%).WithrespecttoTrainoffourstimulationGroupBshoweddecreasedresponsetoneuromuscularstimulationfrom3minutesonwardscomparedtoGroupA.Bispectralindexmonitoring,inbothgroups,showedadecreasingtrendateverytimeinterval.Conclusion:Cisatracuriumisapotentnon-depolarisingneuromuscularblockingagentandtrachealintubationcanbeaccomplishedwithgoodtoexcellentintubatingconditionsaccordingtoSteyn’sModificationofHelbo-HansenScoringSystemat3minutesfollowing0.15mg/kgand0.2mg/kgofCisatracurium.Fromthestudyof100patientsin2groups,wefoundthatCisatracuriuminadoseof3ED95(0.15mg/kg)hashaemodynamicstabilityinviewofHeartrateandBloodPressure.Cisatracuriumatadoseof0.2mg/kgwasmorehaemodynamicallystablethanCisatracuriumat0.15mg/kgduringintubation.
Authors and Affiliations
Kiran Chheda , Vyank atesh Munje, Alka Halbe
Keywords
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- EP ID EP739776
- DOI 10.47191/ijmscrs/v3-i2-02
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